251647-53-7

Basic information

• Product Name: 2'-O-MOE-A(Bz)-3'-phosphoramidite
• Synonyms: 2'-O-MOE-A(Bz)-3'-phosphoramidite;N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];ADENOSINE, N-BENZOYL-5'-O-[BIS(4-METHOXYPHENYL)PHENYLMETHYL]-2'-O-(2-METHOXYETHYL)-, 3'-[2-CYANOETHYL BIS(1-METHYLETHYL)PHOSPHORAMIDITE] (9CI);2'-O-MOE-Bz-A Phosphoramidite;N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine 3'-CE phosphoramidite;2'-O-MOE-A(Bz)-CE Phosphoramidite
• CAS NO: 251647-53-7
• Molecular Formula: C50H58N7O9P
• Molecular Weight: 932.01
• Mol File: 251647-53-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-O-MOE-A(Bz)-3'-phosphoramidite(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-O-MOE-A(Bz)-3'-phosphoramidite(251647-53-7)
• EPA Substance Registry System: 2'-O-MOE-A(Bz)-3'-phosphoramidite(251647-53-7)

Safety Data

• Hazardous Substances Data: 251647-53-7(Hazardous Substances Data)

Usage

Description

2'-O-MOE-A(Bz)-3'-phosphoramidite is a chemical compound that is utilized in the synthesis of oligonucleotides. It is characterized by its unique structure, which includes a 2'-O-(2-methoxyethyl) modification on the adenosine base and a benzoyl group attached to the N6 position. 2'-O-MOE-A(Bz)-3'-phosphoramidite is known for its role in the development of modified oligonucleotides with enhanced properties and applications in various fields.

Uses

Used in Diagnostic Applications:
2'-O-MOE-A(Bz)-3'-phosphoramidite is used as a key component in the synthesis of oligonucleotidic modulators for diagnostic purposes. It is particularly useful in the screening of insulin-like growth factor-I (IGF-I) and growth hormone receptor (GHR) modulators, which are essential for understanding the regulation of growth and development in various organisms.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2'-O-MOE-A(Bz)-3'-phosphoramidite is used as a building block for the development of modified oligonucleotides with improved stability, specificity, and affinity for their target molecules. These modified oligonucleotides can be employed as therapeutic agents for various diseases, including genetic disorders and cancer.
Used in Research and Development:
2'-O-MOE-A(Bz)-3'-phosphoramidite is also used in research and development for the design and synthesis of novel oligonucleotides with specific properties and functions. 2'-O-MOE-A(Bz)-3'-phosphoramidite can be incorporated into the oligonucleotide sequence to enhance its performance in various applications, such as gene regulation, drug delivery, and molecular diagnostics.