25176-55-0Relevant articles and documents
Ferric Salt Catalyzed Oxygenation of Cycloalkanones to Oxo Esters by Molecular Oxygen
Ito, Satoru,Matsumoto, Masakatsu
, p. 1133 - 1135 (1983)
Ferric salts catalyzed the regiospecific oxygenation of cycloalkanones by molecular oxygen to give oxo esters in the presence of aliphatic alcohol under mild conditions.
LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS
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Page/Page column 98, (2015/07/07)
This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R4, n and p are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
Introducing an in situ capping strategy in systems biocatalysis to access 6-aminohexanoic acid
Sattler, Johann H.,Fuchs, Michael,Mutti, Francesco G.,Grischek, Barbara,Engel, Philip,Pfeffer, Jan,Woodley, John M.,Kroutil, Wolfgang
supporting information, p. 14153 - 14157 (2015/02/19)
The combination of two cofactor self-sufficient biocatalytic cascade modules allowed the successful transformation of cyclohexanol into the nylon-6 monomer 6-aminohexanoic acid at the expense of only oxygen and ammonia. A hitherto unprecedented carboxylic acid capping strategy was introduced to minimize the formation of the deadend intermediate 6-hydroxyhexanoic acid. For this purpose, the precursor ε-caprolactone was converted in aqueous medium in the presence of methanol into the corresponding methyl ester instead of the acid. Hence, it was shown for the first time that esterases-specifically horse liver esterase-can perform the selective ring-opening of ε-caprolactone with a clear preference for methanol over water as the nucleophile.
