25178-38-5 Usage
Description
2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID, also known as α-Amino-2-hydroxybenzeneacetic Acid, is an organic compound with a unique molecular structure that features an amino group and a hydroxyphenyl group. It is characterized by its potential biological activities and applications in various fields, particularly in the pharmaceutical and medical industries.
Uses
Used in Pharmaceutical Industry:
2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID is used as a therapeutic agent for the treatment, prevention, or improvement of nonalcoholic fatty liver disease (NAFLD). Its application is based on its ability to modulate the underlying metabolic pathways and biochemical processes associated with the development and progression of NAFLD.
Used in Research and Development:
In addition to its pharmaceutical applications, 2-AMINO-2-(2-HYDROXYPHENYL)ACETIC ACID is also utilized as a research compound for studying the molecular mechanisms and pathophysiology of various diseases, particularly those related to metabolic and liver disorders. Its use in research aids in the development of novel therapeutic strategies and drug candidates for the treatment of such conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 25178-38-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,1,7 and 8 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 25178-38:
(7*2)+(6*5)+(5*1)+(4*7)+(3*8)+(2*3)+(1*8)=115
115 % 10 = 5
So 25178-38-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO3/c9-7(8(11)12)5-3-1-2-4-6(5)10/h1-4,7,10H,9H2,(H,11,12)
25178-38-5Relevant articles and documents
Synthesis of Unprotected 2-Arylglycines by Transamination of Arylglyoxylic Acids with 2-(2-Chlorophenyl)glycine
Inada, Haruki,Shibuya, Masatoshi,Yamamoto, Yoshihiko
, p. 11047 - 11059 (2020/10/12)
The transamination of α-keto acids with 2-phenylglycine is an effective methodology for directly synthesizing unprotected α-amino acids. However, the synthesis of 2-arylglycines by transamination is problematic because the corresponding products, 2-arylglycines, transaminate the starting arylglyoxylic acids. Herein, we demonstrate the use of commercially available l-2-(2-chlorophenyl)glycine as the nitrogen source in the transamination of arylglyoxylic acids, producing the corresponding 2-arylglycines without interference from the undesired self-transamination process.
2-HYDROXYPHENYLALKYLAMINE DERIVATIVES AND MAILLARD REACTION INHIBITORS
-
, (2008/06/13)
The present invention relates to a 2-hydroxyphenyl alkylamine derivative represented by the general formula: wherein R1, R2, R3and R4are the same or different: and each represents a hydrogen atom, a lower alkyl
HYDROXYLATION REACTION OF AROMATIC RINGS IN AQUEOUS SOLUTION INDUCED BY HYDROGEN-OXYGEN FLAME
Takasaki, Michiaki,Nomoto, Shinya,Harada, Kaoru
, p. 1629 - 1632 (2007/10/02)
It was found that direct hydroxylation of aromatic rings proceeded in aqueous solution of phenyl-containing amino acids by using hydrogen-oxygen flame and that the active species of the reaction could be considered as hydroxyl radicals generated in the burning flame.
