252742-73-7

Basic information

• Product Name: 3-((benzyloxy)methyl)-1H-1,2,4-triazol-5(4H)-one
• Synonyms: 3-((benzyloxy)methyl)-1H-1,2,4-triazol-5(4H)-one
• CAS NO: 252742-73-7
• Molecular Weight: 205.216
• Mol File: 252742-73-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-((benzyloxy)methyl)-1H-1,2,4-triazol-5(4H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((benzyloxy)methyl)-1H-1,2,4-triazol-5(4H)-one(252742-73-7)
• EPA Substance Registry System: 3-((benzyloxy)methyl)-1H-1,2,4-triazol-5(4H)-one(252742-73-7)

Safety Data

• Hazardous Substances Data: 252742-73-7(Hazardous Substances Data)

Upstream product

• 19810-31-2 Benzyloxyacetyl chloride 
• 563-41-7 semicarbazide hydrochloride 

Relevant articles and documents

A new synthesis of 1,2,4-triazolin-5-ones: Application to the convergent synthesis of an NK1 antagonist

Chlorotriazolinone 4 has been synthesised in a single step via the novel condensation of semicarbazide hydrochloride with orthoester 8. Alkylation of secondary amine 3 with compound 4 proceeds in 99% yield to afford the target NK1 antagonist 1. (C) 2000 Published by Elsevier Science Ltd.

Chemical synthesis of morpholine derivatives

The present invention relates to a process for the preparation of mopholine derivatives of formula (I) which are useful as a therapeutic agents.