2528-00-9 Usage
Description
ETHYL 5-(CHLOROMETHYL)-2-FURANCARBOXYLATE is a clear yellow liquid that serves as a key intermediate in the synthesis of various chemical compounds, particularly in the pharmaceutical industry. Its unique chemical structure allows for the creation of novel sulfamideand urea-based small-molecule antagonists, making it a valuable component in drug development.
Uses
Used in Pharmaceutical Industry:
ETHYL 5-(CHLOROMETHYL)-2-FURANCARBOXYLATE is used as a starting material for the synthesis of 5-hydroxymethylfuran-2-carboxylic acid, which is essential in the development of new pharmaceutical compounds.
Used in the Synthesis of Antagonists:
In the field of protein-protein interaction research, ETHYL 5-(CHLOROMETHYL)-2-FURANCARBOXYLATE is used as a starting material for the synthesis of novel sulfamideand urea-based small-molecule antagonists of the protein-protein interaction IL-2/IL-2Rα. These antagonists have potential applications in the treatment of various diseases and conditions related to the immune system.
Used in Chemical Research and Development:
As a clear yellow liquid with unique chemical properties, ETHYL 5-(CHLOROMETHYL)-2-FURANCARBOXYLATE is also used in various chemical research and development projects, where it can be further modified or combined with other compounds to create new materials or products with specific applications in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 2528-00-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,5,2 and 8 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2528-00:
(6*2)+(5*5)+(4*2)+(3*8)+(2*0)+(1*0)=69
69 % 10 = 9
So 2528-00-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H9ClO3/c1-2-11-8(10)7-4-3-6(5-9)12-7/h3-4H,2,5H2,1H3
2528-00-9Relevant articles and documents
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Haworth,Jones
, p. 667,670 (1944)
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PREPARATION OF ACID CHLORIDES FROM 5-(CHLOROMETHYL) FURFURAL
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, (2016/12/22)
Acid chloride derivatives of 5-(chloromethyl)furan-2-carboxylic acid and furan-2,5-dicarboxylic acid (FDCA) can be produced in high yield by treatment of the precursor aldehydes 5-(chloromethyl)furfural (CMF) and 2,5-diformylfuran (DFF) with tert-butyl hypochlorite, which is inexpensively prepared from commercial bleach and tert-butanol. 5-(Chloromethyl)furan-2-carbonyl chloride (CMFCC) and furan-2,5-dicarbonyl chloride (FDCC) are highly useful intermediates for the production of furoate ester biofuels and polymers of FDCA.
A new synthesis of 8-oxabicyclo[3.2.1]octan-2-one and its use for the preparation of cycloheptane annulated furans
Hopf, Henning,Abhilash
scheme or table, p. 3349 - 3351 (2010/03/04)
Two novel syntheses of 8-oxabicyclo[3.2.1]octan-2-one are described, making this key intermediate readily available in preparative amounts. On chain elongation with various oxophosphonates this compound is converted to α,β-unsaturated ketones, which, on t
