2528-30-5

Basic information

• Product Name: 4-{[(benzyloxy)carbonyl](methyl)amino}benzoic acid
• CAS NO: 2528-30-5
• Molecular Formula: C₁₆H₁₅NO₄
• Molecular Weight: 285.2946
• Mol File: 2528-30-5.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 473.1°C at 760 mmHg
• Flash Point: 239.9°C
• Density: 1.292g/cm³
• Vapor Pressure: 9.35E-10mmHg at 25°C
• Refractive Index: 1.628
• CAS DataBase Reference: 4-{[(benzyloxy)carbonyl](methyl)amino}benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(benzyloxy)carbonyl](methyl)amino}benzoic acid(2528-30-5)
• EPA Substance Registry System: 4-{[(benzyloxy)carbonyl](methyl)amino}benzoic acid(2528-30-5)

Safety Data

• Hazardous Substances Data: 2528-30-5(Hazardous Substances Data)

Upstream product

• 10541-83-0 N-methyl-p-aminobenzoic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 875668-13-6 2-({(S)-3-[4-(Benzyloxycarbonyl-methyl-amino)-benzoylamino]-3-methoxycarbonyl-propyl}-methoxy-phosphinoylmethyl)-pentanedioic acid dimethyl ester 
• 875668-14-7 2-({3-[4-(benzyloxycarbonyl-methyl-amino)-benzoylamino]-3-tert-butoxycarbonyl-propyl}-methoxy-phosphinoylmethyl)-pentanedioic acid di-tert-butyl ester 
• 875668-08-9 methyl (2S)-4-bromo-2-N-[4-(N-benzyloxycarbonyl-N-methyl)aminobenzoyl]aminobutyrate 
• 875667-97-3 (4-azidocarbonyl-phenyl)-methyl-carbamic acid benzyl ester 
• 1177418-21-1 C₃₇H₅₄N₄O₁₁ 
• 1177418-07-3 C₃₇H₅₄N₄O₁₁ 
• 1177418-15-3 C₅₆H₈₀N₈O₁₅ 
• 329365-33-5 4-[N-(benzyloxycarbonyl)-N-methylamino]-N'-tert-butylbenzamide 
• 92215-59-3 2-{4-[(2,4-Diamino-pteridin-6-ylmethyl)-methyl-amino]-benzoylamino}-4-(diethoxy-phosphoryl)-butyric acid ethyl ester 
• 93960-33-9 [3-{4-[(5-Amino-6-cyano-pyrazin-2-ylmethyl)-methyl-amino]-benzoylamino}-3-(diethoxy-phosphoryl)-propyl]-phosphonic acid diethyl ester 
• 93960-31-7 2-{4-[(5-Amino-6-cyano-pyrazin-2-ylmethyl)-methyl-amino]-benzoylamino}-4-(diethoxy-phosphoryl)-butyric acid ethyl ester 
• 93960-32-8 4-{4-[(5-Amino-6-cyano-pyrazin-2-ylmethyl)-methyl-amino]-benzoylamino}-4-(diethoxy-phosphoryl)-butyric acid methyl ester 
• 93960-30-6 [3-(Diethoxy-phosphoryl)-3-(4-methylamino-benzoylamino)-propyl]-phosphonic acid diethyl ester 
• 93960-28-2 4-(Diethoxy-phosphoryl)-2-(4-methylamino-benzoylamino)-butyric acid ethyl ester 

Relevant articles and documents

ANTIFOLATE-CARRYING NANOPARTICLES AND THEIR USE IN MEDICINE

The present invention provides a nanoparticle comprising: a core comprising a metal and/or a semiconductor; and a plurality of ligands covalently linked to the core, wherein said ligands comprise: (i) at least one dilution ligand comprising a carbohydrate, glutathione or an ethylene glycol-containing moiety; and (ii) a ligand of the formula D-L1-Z-L2, wherein D comprises an antifolate drug or folic acid, L1 comprises a first linker portion comprising a C2-C12 glycol and/or C2-C12 alkyl chain, L2 comprises a second linker portion comprising a C2-C12 glycol and/or C2-C12 alkyl chain, wherein L1 and L2 may be the same or different, and wherein Z represents a carbonyl-containing group linking L1 and L2, and wherein L2 is coupled to said core, Also provided are pharmaceutical compositions comprising such nanoparticles, medical uses thereof and methods for producing the nanoparticles.

PYRAZOLE COMPOUNDS AND THIAZOLE COMPOUNDS AS PROTEIN KINASES INHIBITORS

A compound of formula (I): wherein A, B, D, X, Y, R1, R2, R3, m, p, and q are defined herein. Also disclosed is a method for inhibiting FMS-like tyrosine kinase 3, aurora kinase, or vascular endothelial growth factor receptor.

Helical structures of N-alkylated poly(p-benzarnide)s

Poly(p-benzamide)s 1 bearing a chiral side chain on the nitrogen atom were synthesized by chain-growth polycondensation methodology. The polyamides exhibited well-defined molecular weights with narrow polydispersities. Solutions of the polyamides in sever