25283-98-1

Basic information

• Product Name: 3-(3-NITROPHENYL)-5-METHYL OXADIAZOLE
• Synonyms: 5-methyl-3-(3-nitrophenyl)-1,2,4-oxadiazole;3-(3-NITROPHENYL)-5-METHYL OXADIAZOLE;3-(3-Nitrophenyl)-5-methyl-1,2,4-oxadiazole
• CAS NO: 25283-98-1
• Molecular Formula: C₉H₇N₃O₃
• Molecular Weight: 205.17
• Mol File: 25283-98-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 367.9°C at 760 mmHg
• Flash Point: 176.3°C
• Appearance: /
• Density: 1.349g/cm³
• Vapor Pressure: 2.8E-05mmHg at 25°C
• Refractive Index: 1.581
• PKA: -1.11±0.32(Predicted)
• CAS DataBase Reference: 3-(3-NITROPHENYL)-5-METHYL OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-NITROPHENYL)-5-METHYL OXADIAZOLE(25283-98-1)
• EPA Substance Registry System: 3-(3-NITROPHENYL)-5-METHYL OXADIAZOLE(25283-98-1)

Safety Data

• Hazardous Substances Data: 25283-98-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H7N3O3/c1-6-10-9(11-15-6)7-3-2-4-8(5-7)12(13)14/h2-5H,1H3

Upstream product

• 3717-29-1 E-3-nitrobenzaldoxime 
• 75-05-8 acetonitrile 
• 100-47-0 benzonitrile 
• 99-61-6 3-nitro-benzaldehyde 
• 5023-94-9 3-nitrobenzamidoxime 
• 619-24-9 3-nitrobenzonitrile 
• 134285-42-0 C₉H₉N₃O₄ 
• 5023-94-9 m-nitrobenzamide oxime 
• 123-54-6 acetylacetone 
• 1198-98-7 5-methyl-3-phenyl-1,2,4-oxadiazole 
• 108-22-5 Isopropenyl acetate 

Downstream Products

• 98802-73-4 5,5'-dimethyl-3,3'-(3,3'-oxydiazenediyl-diphenyl)-bis-[1,2,4]oxadiazole 
• 10185-69-0 3-(5-methyl-[1,2,4]oxadiazol-3-yl)-aniline 

Relevant articles and documents

Synthesis of 3,5-disubstituted-1,2,4-oxadiazoles using tetrabutylammonium fluoride as a mild and efficient catalyst

Tetrabutylammonium fluoride (TBAF) was found to be a mild and efficient catalyst for the synthesis of 3,5-disubstituted-1,2,4-oxadiazoles. Using 0.1 - 1.0 equivalents of TBAF in THF for 1 - 24 h at room temperature, alkanoyl- and aroyloxyamidines were converted in high yield to the corresponding 3,5-disubstituted-1,2,4-oxadiazoles. A variety of R and R′ substituents were investigated.

Ceric ammonium nitrate oxidation of aldoximes in aliphatic nitriles as solvents: A new way for synthesis of 1,2,4-oxadiazoles

Oxidation of aromatic aldoximes with one-electron oxidant ceric ammonium nitrate CAN in acetonitrile and propionitrile, has been investigated. Aromatic nitrile oxides, formed in situ, underwent 1,3-cycloaddition with aliphatic nitriles and 5-alkyl-3-aryl-1,2,4-oxadiazoles are produced in moderate to high yields. The mechanism of the reaction based on the transformations of intermediate aldazine di-N-oxides is discussed.