252869-48-0

Basic information

• Product Name: 3-Methyl-3-[(Z)-6-(phenylsulfenyl)hex-1-enyl]cyclohexa-1,4-diene
• Synonyms: 3-Methyl-3-[(Z)-6-(phenylsulfenyl)hex-1-enyl]cyclohexa-1,4-diene
• CAS NO: 252869-48-0
• Molecular Weight: 284.466
• Mol File: 252869-48-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Methyl-3-[(Z)-6-(phenylsulfenyl)hex-1-enyl]cyclohexa-1,4-diene(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-3-[(Z)-6-(phenylsulfenyl)hex-1-enyl]cyclohexa-1,4-diene(252869-48-0)
• EPA Substance Registry System: 3-Methyl-3-[(Z)-6-(phenylsulfenyl)hex-1-enyl]cyclohexa-1,4-diene(252869-48-0)

Safety Data

• Hazardous Substances Data: 252869-48-0(Hazardous Substances Data)

Upstream product

• 882-33-7 diphenyldisulfane 
• 181576-34-1 (Z)-6-(1-Methylcyclohexa-2,5-dienyl)hex-5-en-1-ol 
• 1014-93-3 1-(benzyloxy)-5-bromopentane 
• 152455-13-5 1-methyl-2,5-cyclohexadiene-1-carboxaldehyde 

Downstream Products

• 181576-35-2 3-Methyl-3-[(Z)-6-(phenylsulfenyl)hex-1-enyl]cyclohexa-1,4-diene 

Relevant articles and documents

Hexamethyldisilazanes mediated one-pot intramolecular Michael addition-olefination reactions leading to exo-olefinated bicyclo[6.4.0]dodecanes

A novel one-pot reaction for the synthesis of exo-olefinated bicyclo[6.4.0]dodecanes 23 has been developed on the basis of an intramolecular Michael reaction of phenylsulfonyl compounds 4 with potassium hexamethyldisilazide (KHMDS) and a sequential reaction with an excess of methoxymethyl chloride (MOMCl). By this reaction, an exo-olefin group was regioselectively introduced at the α-position to the carbonyl group in the 6-membered ring in high yield. The regioselective introduction of the olefin moiety could be envisaged to proceed through a Mannich-type reaction involving the aminomethylating agent 24, which, in turn, is generated in situ by the action of HMDS on MOMCl. The Royal Society of Chemistry 1999.