25315-18-8Relevant articles and documents
The development of novel and selective p56(lck) tyrosine kinase inhibitors
Bullington, James L.,Cameron, Julie C.,Davis, Janet E.,Dodd, John H.,Harris, Crafford A.,Henry, James R.,Pellegrino-Gensey, J. Lee,Rupert, Kenneth C.,Siekierka, John J.
, p. 2489 - 2494 (1998)
Early T-cell receptor mediated signal transduction involves the activation of several tyrosine protein kinases. One of these tyrosine kinases, p56(lck), is expressed primarily in T-cells and Natural Killer (NK) cells and has been shown to be critical for