253435-21-1

Basic information

• Product Name: 2-(3-phenylprop-1-yn-1-yl)benzonitrile
• Synonyms: 2-(3-phenylprop-1-yn-1-yl)benzonitrile
• CAS NO: 253435-21-1
• Molecular Weight: 217.27
• Mol File: 253435-21-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(3-phenylprop-1-yn-1-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-phenylprop-1-yn-1-yl)benzonitrile(253435-21-1)
• EPA Substance Registry System: 2-(3-phenylprop-1-yn-1-yl)benzonitrile(253435-21-1)

Safety Data

• Hazardous Substances Data: 253435-21-1(Hazardous Substances Data)

Upstream product

• 557-21-1 dicyanozinc 
• 253435-17-5 2-(3-phenyl-1-propynyl)-1-iodobenzene 
• 401636-52-0 di-tert-butyl 4-benzyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 1557159-30-4 1-((2-cyanophenyl)ethynyl)-1,2-benziodoxol-3(1H)-one 
• 10147-11-2 propargyl benzene 
• 615-42-9 1,2-Diiodobenzene 

Relevant articles and documents

Application of Hantzsch Ester and Meyer Nitrile in Radical Alkynylation Reactions

The first example of constructing a Csp3-Csp bond with substituted Hantzsch ester and Meyer nitrile is reported. When benziodoxole-activated alkyne was applied as the alkynyl donor, products containing Csp3-Csp bonds involving primary, secondary, and tertiary carbon centers were achieved in up to 97% yields. K2S2O8 was the optimum radical initiator in this reaction.