25372-10-5

Basic information

• Product Name: 1H-Imidazole,1-(4-methylphenyl)-
• Synonyms: Imidazole,1-p-tolyl- (8CI);1-(4-Methylphenyl)-1H-imidazole;1-p-Tolylimidazole;N-(4-Methylphenyl)imidazole
• CAS NO: 25372-10-5
• Molecular Formula: C₁₀H₁₀N₂
• Molecular Weight: 158.203
• Mol File: 25372-10-5.mol
• Article Data: 157

Chemical Properties

• Boiling Point: 287.9 °C at 760 mmHg
• Flash Point: 127.9 °C
• Density: 1.04 g/cm³
• CAS DataBase Reference: 1H-Imidazole,1-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole,1-(4-methylphenyl)-(25372-10-5)
• EPA Substance Registry System: 1H-Imidazole,1-(4-methylphenyl)-(25372-10-5)

Safety Data

• Hazardous Substances Data: 25372-10-5(Hazardous Substances Data)

Usage

General Description

1H-Imidazole,1-(4-methylphenyl)-, also known as p-methylphenylimidazole, is a chemical compound with the molecular formula C10H10N2. It is a derivative of imidazole containing a 4-methylphenyl substituent. 1H-Imidazole,1-(4-methylphenyl)- is used in various pharmaceutical and chemical applications, including as a building block for the synthesis of other organic compounds. It is also utilized as a corrosion inhibitor, a stabilizer for plastics, and as an intermediate in the production of agricultural chemicals. Additionally, this chemical has potential applications in the field of medicinal chemistry, such as in the development of novel drugs and pharmaceutical formulations.

Upstream product

• 288-32-4 1H-imidazole 
• 3076-56-0 p-tolyllead triacetate 
• 106-49-0 p-toluidine 
• 5142-75-6 tri(p-tolyl)bismuth 
• 132680-48-9 O-4-methylphenyl N,N-diethylcarbamate 
• 1205-61-4 p-tolyl N,N-dimethylsulfamate 
• 106-44-5 p-cresol 
• 66117-64-4 di(p-tolyl)borinic acid 
• 624-31-7 4-tolyl iodide 
• 50-00-0 formaldehyd 
• 174647-97-3 [(Z)-p-Tolylimino]-acetaldehyde 
• 131543-46-9 Glyoxal 
• 106-38-7 para-bromotoluene 
• 106-43-4 para-chlorotoluene 

Downstream Products

• 1263043-79-3 C₃₆H₃₉N₇ 
• 1176199-92-0 1-(4-methylphenyl)-3-hexyl-1H-imidazolium bromide 
• 1176198-73-4 1-(4-methylphenyl)-3-propyl-1H-imidazolium bromide 
• 1286795-79-6 1-(4-methylphenyl)-3-heptyl-1H-imidazolium bromide 
• 1176198-87-0 3-ethyl-1-(p-tolyl)-1H-imidazol-3-ium bromide 

Relevant articles and documents

Synthesis and Physical Properties of Tunable Aryl Alkyl Ionic Liquids (TAAILs)

Tunable aryl alkyl ionic liquids (TAAILs) based on the imidazolium cation were first reported in 2009. Since then, a series of TAAILs with different properties due to the electron-donating or -withdrawing effect of the substituents at the aryl ring has be

Functionalization of superparamagnetic Fe3O4@SiO2 nanoparticles with a Cu(II) binuclear Schiff base complex as an efficient and reusable nanomagnetic catalyst for N-arylation of α-amino acids and nitrogen-containing heterocycles with aryl halides

Fe3O4@SiO2 nanoparticles was functionalized with a binuclear Schiff base Cu(II)-complex (Fe3O4@SiO2/Schiff base-Cu(II) NPs) and used as an effective magnetic hetereogeneous nanocatalyst for the N-arylation of α-amino acids and nitrogen-containig heterocycles. The catalyst, Fe3O4@SiO2/Schiff base-Cu(II) NPs, was characterized by Fourier transform infrared (FTIR) and ultraviolet-visible (UV-vis) analyses step by step. Size, morphology, and size distribution of the nanocatalyst were studied by transmission electron microscopy (TEM), scanning electron microscopy (SEM), and dynamic light scatterings (DLS) analyses, respectively. The structure of Fe3O4 nanoparticles was checked by X-ray diffraction (XRD) technique. Furthermore, the magnetic properties of the nanocatalyst were investigated by vibrating sample magnetometer (VSM) analysis. Loading content as well as leaching amounts of copper supported by the catalyst was measured by inductive coupled plasma (ICP) analysis. Also, thermal studies of the nanocatalyst was studied by thermal gravimetric analysis (TGA) instrument. X-ray photoelectron spectroscopy (XPS) analysis of the catalyst revealed that the copper sites are in +2 oxidation state. The Fe3O4@SiO2/Schiff base-Cu(II) complex was found to be an effective catalyst for C–N cross-coupling reactions, which high to excellent yields were achieved for α-amino acids as well as N-hetereocyclic compounds. Easy recoverability of the catalyst by an external magnet, reusability up to eight runs without significant loss of activity, and its well stability during the reaction are among the other highlights of this catalyst.

Tunable aryl imidazolium ionic liquids (TAIILs) as environmentally benign catalysts for the esterification of fatty acids to biodiesel fuel

Herein, we describe the synthesis of tunable aryl imidazolium ionic liquid catalysts and tested for esterification of fatty acids to biodiesel. In this work, six tunable aryl imidazolium ionic liquids (TAIILs) 1a-1f were prepared. These ionic liquids were used as the economical and reusable catalysts for the synthesis of biodiesel fuels. The reaction has been preceded in a monophase at 80 °C for 4 h, after which the product was separated from the catalyst system by a simple liquid/liquid phase separation at room temperature with excellent yields. With the simple post-process, the catalyst is reusable at least 6 times. This novel method offers a short reaction time, good yields, and environmentally benign characteristics.