25394-57-4 Usage
Description
N-ISOBUTYL-2,6,8-DECATRIENAMIDE, also known as Spilanthol, is a fatty acid amide derived from the plant Acmella oleracea. It is characterized by its unique chemical structure, which includes an isobutyl group and three conjugated double bonds in its alkenamide chain. N-ISOBUTYL-2,6,8-DECATRIENAMIDE has been found to possess various biological activities, making it a potential candidate for pharmaceutical and industrial applications.
Uses
Used in Pharmaceutical Applications:
N-ISOBUTYL-2,6,8-DECATRIENAMIDE is used as a therapeutic agent for treating dry mouth (xerostomia). It acts as a saliva stimulant (sialogogue), helping to alleviate the symptoms of xerostomia by promoting saliva production in individuals suffering from this condition.
Used in Flavor and Fragrance Industry:
N-ISOBUTYL-2,6,8-DECATRIENAMIDE is used as a flavoring agent for its unique taste and aroma. Its distinct properties make it a valuable addition to the flavor and fragrance industry, where it can be used to enhance the sensory experience of various products.
Used in Cosmetics and Personal Care:
N-ISOBUTYL-2,6,8-DECATRIENAMIDE is used as an active ingredient in cosmetics and personal care products due to its potential benefits for skin health. Its biological activities may contribute to improved skin hydration, reduced inflammation, and enhanced skin barrier function.
Used in Agrochemicals:
N-ISOBUTYL-2,6,8-DECATRIENAMIDE can be used as a bioactive compound in the development of agrochemicals, such as pesticides and herbicides. Its unique chemical structure and biological activities may provide novel modes of action for controlling pests and weeds in agriculture.
Synthesis Reference(s)
Tetrahedron Letters, 25, p. 5177, 1984 DOI: 10.1016/S0040-4039(01)81556-2
Check Digit Verification of cas no
The CAS Registry Mumber 25394-57-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,3,9 and 4 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 25394-57:
(7*2)+(6*5)+(5*3)+(4*9)+(3*4)+(2*5)+(1*7)=124
124 % 10 = 4
So 25394-57-4 is a valid CAS Registry Number.
InChI:InChI=1/C14H23NO/c1-4-5-6-7-8-9-10-11-14(16)15-12-13(2)3/h4-7,10-11,13H,8-9,12H2,1-3H3,(H,15,16)/b5-4+,7-6-,11-10+
25394-57-4Relevant articles and documents
Efficient Preparation of Functionalized (E,Z) Dienes Using Acetylene as the Building Block
Wang, Zhong,Lu, Xiyan,Lei, Aiwen,Zhang, Zhaoguo
, p. 3806 - 3807 (1998)
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METHOD FOR MANUFACTURING SPILANTHOL AND INTERMEDIATE MANUFACTURING PRODUCT THEREFOR
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Page/Page column 6, (2012/05/20)
Provided is an amide ester that is useful as an intermediate manufacturing product for an aroma compound such as spilanthol or the like. Also provided is a spilanthol manufacturing method using said amide ester. High-purity spilanthol can be manufactured by reacting an amide ester represented by general formula (1) with a basic compound. (In the formula, R1 represents a phenyl group that may be substituted with a C1-6 alkyl group and either a C1-4 alkyl group, a C1-4 alkoxy group, or a halogen atom; R2 represents a C1-8 hydrocarbon group; and the wavy lines represent cis configurations, trans configurations, or a mixture of the two configurations.)
FACILE R0UTES TO NATURAL ACYCLIC POLIENES. SYNTHESES OF SPILANTHOL AND TRAIL PHEROMONE FOR TERMITE
Ikeda, Yoshihiko,Ukai, Junzo,Ikeda, Nobuo,Yamamoto, Hisashi
, p. 5177 - 5180 (2007/10/02)
The synthetic procedures for spilanthol and trail-following pheromone for a southern subterranean termite were described.The syntheses heavily depend on the new diene synthesis using titanium reagent.
