25414-22-6

Basic information

• Product Name: 2-METHOXYFURAN
• Synonyms: 2-METHOXYFURAN;2-FURYL METHYL ETHER;2-Methoxyfurane;2-Methoxyfuran,97%;2-Methoxyfuran, 97% 5GR;2-Methoxyfuran 97%
• CAS NO: 25414-22-6
• Molecular Formula: C₅H₆O₂
• Molecular Weight: 98.1
• EINECS: 246-953-8
• Product Categories: Heterocycles;Building Blocks;Furans;Heterocyclic Building Blocks;Building Blocks;C4 to C7;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 25414-22-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 110-111°C
• Flash Point: 50 °F
• Appearance: /
• Density: 1.065 g/mL at 25 °C(lit.)
• Vapor Pressure: 27.8mmHg at 25°C
• Refractive Index: n20/D 1.447(lit.)
• Storage Temp.: 0-6°C
• BRN: 106270
• CAS DataBase Reference: 2-METHOXYFURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXYFURAN(25414-22-6)
• EPA Substance Registry System: 2-METHOXYFURAN(25414-22-6)

Safety Data

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-29-33
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 25414-22-6(Hazardous Substances Data)

Usage

Description

2-Methoxyfuran is an organic compound characterized by its clear light yellow liquid appearance. It is known for its ability to form cycloadducts with maleic anhydride and N-methylmaleimide, as well as undergoing Friedel-Crafts reactions with nitroalkenes catalyzed by specific complexes.

Uses

Used in Chemical Synthesis:
2-Methoxyfuran is used as a chemical intermediate for the synthesis of various furan derivatives. Its reactivity in forming cycloadducts and undergoing Friedel-Crafts reactions makes it a valuable compound in the development of new chemical products and materials.
Used in Research and Development:
2-Methoxyfuran is utilized in academic and industrial research for studying the hydrolysis of furan derivatives through acid catalysis. This application aids in understanding the chemical behavior of furan compounds and their potential applications in various fields.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 2-Methoxyfuran may also find applications in the pharmaceutical industry due to its chemical properties and reactivity. It could potentially be used in the synthesis of drug molecules or as a building block for developing new pharmaceutical compounds.

InChI:InChI=1/C5H6O2/c1-6-5-3-2-4-7-5/h2-4H,1H3

Upstream product

• 53869-94-6 Methyl 5-methoxy-2-furancarboxylate 
• 332-77-4 2,5-dihydro-2,5-dimethoxyfuran 
• 584-12-3 2-bromofuran 
• 124-41-4 sodium methylate 
• 94084-62-5 5-methoxy-furan-2-carboxylic acid 

Downstream Products

• 157252-33-0 5-aminoquinoline-8-carboxylic acid methyl ester 
• 157252-30-7 8-Amino-isoquinoline-5-carboxylic acid methyl ester 
• 157252-27-2 methyl 7-amino-1-benzofuran-4-carboxylate 
• 157252-28-3 7-Amino-benzo[b]thiophene-4-carboxylic acid methyl ester 
• 15852-34-3 2,5-dihydroxycyclohepta-2,4,6-trien-1-one 
• 105664-52-6 (Z)-methyl 3-<4,6-dichloro-2,3-dihydro-3-(4-nitrobenzoyl)-2-benzoxazolyl>-2-propenate 
• 72541-79-8 methyl (2,3,4,5-tetrachlorophenyl)acetate 
• 75445-67-9 5-benzyloxy-4-methoxy-1-naphthalenol 
• 140201-78-1 5-Benzyloxy-8-[(2S,3R,4S,5R)-3,4-bis-benzyloxy-5-((S)-1-benzyloxy-ethyl)-tetrahydro-furan-2-yl]-4-methoxy-naphthalen-1-ol 
• 157252-24-9 methyl 4-aminonaphthalene-1-carboxylate 
• 22481-08-9 2,3-bis(methoxycarbonyl)-4-methoxyphenol 

Relevant articles and documents

Copper(I) Halide Catalysed Synthesis of Alkyl Aryl and Alkyl Heteroaryl Ethers

A number of alkyl aryl and alkyl heteroaryl ethers have been prepared from (hetero) aryl halides (mainly bromides) and sodium alkoxides, using copper(I)bromide as a catalyst.The influence of the main solvent, the halogen atom, reaction temperature and the presence of oxygen upon the rate and selectivity has been studied.Furthermore the decomposition of the catalyst and the reduction of the aryl halide are studied.

Photochemistry. IX. Formation of cyclopropenyl ketones and furans from pyridazine N oxides by irradiation

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