254430-80-3

Basic information

• Product Name: (R)-4-(2-Cyclopentyl-phenoxymethyl)-[1,3,2]dioxathiolane 2-oxide
• Synonyms: (R)-4-(2-Cyclopentyl-phenoxymethyl)-[1,3,2]dioxathiolane 2-oxide
• CAS NO: 254430-80-3
• Molecular Weight: 282.361
• Mol File: 254430-80-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-4-(2-Cyclopentyl-phenoxymethyl)-[1,3,2]dioxathiolane 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-(2-Cyclopentyl-phenoxymethyl)-[1,3,2]dioxathiolane 2-oxide(254430-80-3)
• EPA Substance Registry System: (R)-4-(2-Cyclopentyl-phenoxymethyl)-[1,3,2]dioxathiolane 2-oxide(254430-80-3)

Safety Data

• Hazardous Substances Data: 254430-80-3(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 122030-10-8 Allyl 2-cyclopentylphenyl ether 
• 254430-79-0 (S)-3-(2-Cyclopentyl-phenoxy)-propane-1,2-diol 
• 1518-84-9 2-cyclopentylphenol 
• 96-41-3 Cyclopentanol 

Downstream Products

• 254430-81-4 (R)-4-(2-Cyclopentyl-phenoxymethyl)-[1,3,2]dioxathiolane 2,2-dioxide 
• 38363-40-5 (S)-penbutolol 

Relevant articles and documents

Regioselective alkylation of phenol with cyclopentanol over montmorillonite K10: An efficient synthesis of l-(2-cyclopentylphenoxy)-3-[(l,l-dimethylethyl)amino]propan-2-ol {(S')-penbutolol}

Regioselective alkylation of phenol with cyclopentanol is achieved over Montmorillonite K10 clay, producing 2-cycIopentylphenol, the key intermediate. The synthesis of optically active (S)-penbutoIol 1, an important antihypertensive drug, is realized in 5 steps from 2-cyclopentylphenol by employing Sharpless asymmetric dihydroxylation. The Royal Society of Chemistry 1999.