254729-95-8

Basic information

• Product Name: 1H-Pyrrole-2-carbaldehyde
• Synonyms: 1H-PYRROLE-2-CARBALDEHYDE
• CAS NO: 254729-95-8
• Molecular Formula: C5H5NO
• Molecular Weight: 95.1
• EINECS: 213-705-5
• Mol File: 254729-95-8.mol
• Article Data: 83

Chemical Properties

• Melting Point: 40-47℃
• Boiling Point: 219.1°Cat760mmHg
• Flash Point: 107 °C
• Appearance: /
• Density: 1.197g/cm³
• Vapor Pressure: 0.121mmHg at 25°C
• Refractive Index: 1.607
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1H-Pyrrole-2-carbaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2-carbaldehyde(254729-95-8)
• EPA Substance Registry System: 1H-Pyrrole-2-carbaldehyde(254729-95-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 254729-95-8(Hazardous Substances Data)

Usage

General Description

1H-Pyrrole-2-carbaldehyde is a chemical compound with the chemical formula C6H5NO. It is an aromatic aldehyde that contains a pyrrole ring, which is a five-membered heterocyclic ring with nitrogen atoms. It is used as a building block in organic synthesis and can be used to create a variety of compounds. 1H-Pyrrole-2-carbaldehyde is a yellow liquid with a strong odor, and it is flammable and should be handled with care. It is commonly used in the production of pharmaceuticals, agrochemicals, and dyes. Additionally, it has potential applications in the field of materials science and nanotechnology.

InChI:InChI=1/C5H5NO/c7-4-5-2-1-3-6-5/h1-4,6H

Upstream product

• 80525-78-6 N-((1H-pyrrol-2-yl)methylene)-4-methoxybenzenamine 
• 16851-82-4 N-phenylsulfonylpyrrole 
• 68-12-2 N,N-dimethyl-formamide 
• 121643-36-5 2-Bromo-6-diisopropylamino-1-azafulvene 
• 1236203-44-3 N-(hydroxy-2' ethyl)amino-3 propenoate d'ethyle 
• 83651-28-9 N-Pyrrolylmethylene p-nitroaniline 
• 83651-27-8 pyrrole-2-(N-m-nitrophenyl)aldimine 
• 83651-26-7 N-Pyrrolylmethylene m-cyanoaniline 
• 121529-92-8 2-Dibutoxymethyl-1H-pyrrole 
• 594-19-4 tert.-butyl lithium 
• 917-54-4 methyllithium 
• 82217-94-5 5,6-dihydropyrrolo<1,2-a>azepin-7-one 
• 51305-61-4 N-(pyrrolyl-2-methylene)-p-bromoaniline 
• 51305-60-3 N-(pyrrolyl-2-methylene)-p-chloroaniline 

Downstream Products

• 133305-21-2 Pyrrole-2-(2-imino-1-phenylpropan-1-ol) 
• 1963-42-4 2-(p-methoxybenzyl)pyrrole 
• 2433-65-0 3-(pyrrol-2-yl)acrylic acid ethyl ester 
• 79499-36-8 2-(m-Methoxybenzyl)pyrrole 
• 79499-35-7 2-(2-methoxybenzyl)-1H-pyrrole 
• 79499-34-6 2-(4-methylbenzyl)-1H-pyrrole 
• 90909-81-2 5,6-Dihydro-4-(phenylsulfonyl)pyrrolo<2',1':4,5><1,5>diazocino<2,1,8-c,d>pyrrolizin 
• 90909-82-3 2-(Phenylsulfonyl)-3,3-bis<2-(phenylsulfonyl)ethyl>-3H-pyrrolizin 
• 90909-83-4 6-(Phenylsulfonyl)-5-<2-(phenylsulfonyl)ethyl>-3-<<1-<2-(phenylsulfonyl)ethyl>-2-pyrrolyl>methylen>pyrrolizin 
• 87549-04-0 1-<2-(Phenylsulfonyl)ethyl>-2-pyrrolcarbaldehyd 
• 73217-16-0 1-(2-chloromethyl-benzyl)-pyrrole-2-carbaldehyde 
• 129055-79-4 C₁₈H₁₆N₂O₂ 
• 108320-23-6 8-(4-Methylphenylsulfonyl)-5H-pyrrolo<1,2-a>azepin 
• 2761-76-4 cis-2-styrylpyrrole 

Relevant articles and documents

Highly atom efficient synthesis of 2,2,4,5-tetrasubstituted 3(2H)-furanones having both hydroxyl and amino substituents

We have developed a highly atom efficient synthesis of tetrasubstituted 3(2H)-furanones from easily accessible starting materials such as C,N-diarylaldonitrones and dibenzoylacetylene. Control experiments revealed that reaction of aldonitrones having electron-withdrawing groups on the C-aryl substituent in polar aprotic solvents exhibited high product selectivity while reaction temperature has only a negligible effect on product yield and selectivity.

Synthesis process of retegravir intermediate

The invention relates to a synthesis process of a retegravir intermediate 7-iodine-4-amido pyrrolo [2,1-F] [1, 2, 4] triazine. The method comprises the following steps: by using pyrrole as an initialraw material, carrying out aldehyde groupintroduction through phosphorus oxychloride-DMF to obtain 2-aldehyde group pyrrole; preparing a 2-cyano key intermediate through ammonium sulfate, wherein thesteps is the key step of the process; cyclizing the cyano intermediate and formamidine acetate to prepare a 4-amino intermediate; reacting with NIS and adding iodine to prepare the target compound 7-iodine-4-amido pyrrolo [2,1-F] [1, 2, 4] triazine. The whole process has the advantages of simple and easily available raw materials, simple and easy operation, and very high economic value and socialbenefit.

Investigating Alkylated Prodigiosenes and Their Cu(II)-Dependent Biological Activity: Interactions with DNA, Antimicrobial and Photoinduced Anticancer Activity

Prodigiosenes are a family of red pigments with versatile biological activity. Their tripyrrolic core structure has been modified many times in order to manipulate the spectrum of activity. We have been looking systematically at prodigiosenes substituted