254878-31-4

Basic information

• Product Name: 5-Chloro-2-(4-chloro-phenylsulfonylamino)-benzoyl chloride
• CAS NO: 254878-31-4
• Molecular Weight: 364.636
• Mol File: 254878-31-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-Chloro-2-(4-chloro-phenylsulfonylamino)-benzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Chloro-2-(4-chloro-phenylsulfonylamino)-benzoyl chloride(254878-31-4)
• EPA Substance Registry System: 5-Chloro-2-(4-chloro-phenylsulfonylamino)-benzoyl chloride(254878-31-4)

Safety Data

• Hazardous Substances Data: 254878-31-4(Hazardous Substances Data)

Upstream product

• 136402-32-9 5-chloro-2-{[(4-chlorophenyl)sulfonyl]amino}benzoic acid 

Downstream Products

• 254878-14-3 4-Chloro-N-(2-(1H-benzimidazol-2-yl)-4-chloro-phenyl)-benzenesulfonamide 
• 254878-69-8 3-((5-Chloro-2-(4-chloro-phenylsulfonylamino)-benzoyl)-amino)-benzenesulfonyl fluoride 

Relevant articles and documents

SULFUR SUBSTITUTED SULFONYLAMINOCARBOXYLIC ACID N-ARYLAMIDES, THEIR PREPARATION, THEIR USE AND PHARMACEUTICAL PREPARATIONS COMPRISING THEM

The present invention relates to compounds of the formula I wherein A1, A2, R1, R2, R3, X and n are as defined in the claims, which are valuable pharmaceutically active compounds for the therapy and prophylaxis of diseases, for example of cardiovascular diseases such as hypertension, angina pectoris, cardiac insufficiency, thromboses or atherosclerosis. The compounds of the formula I are capable of modulating the body’s production of cyclic guanosine monophosphate (cGMP) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of the formula I, to their use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of the formula I