2550-89-2

Basic information

• Product Name: 5α-Cholest-7-ene-3,6-dione
• Synonyms: 5α-Cholest-7-ene-3,6-dione
• CAS NO: 2550-89-2
• Molecular Formula: C₂₇H₄₂O₂
• Molecular Weight: 398.62118
• Mol File: 2550-89-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5α-Cholest-7-ene-3,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5α-Cholest-7-ene-3,6-dione(2550-89-2)
• EPA Substance Registry System: 5α-Cholest-7-ene-3,6-dione(2550-89-2)

Safety Data

• Hazardous Substances Data: 2550-89-2(Hazardous Substances Data)

Upstream product

• 2259-91-8 5α-cholest-7-ene-3β,6α-diol 
• 1059-86-5 7-Dehydrocholesteryl acetate 
• 1262677-34-8 (3S, 5S, 6S)-3-Triethylsiloxy-7-cholesten-6-ol 
• 1262677-33-7 (S)-3-Triethylsiloxy-5,7-cholestadiene 
• 14858-06-1 3β-hydroxy-5α-cholest-7-en-6-one 
• 153582-27-5 3,3-(ethylenedioxy)-5α-cholest-7-en-6-one 
• 434-16-2 7-dehydrocholesterol 
• 136985-72-3 3,3-(ethylenedioxy)-5α-cholest-7-en-6α-ol 
• 103326-74-5 3,3-(ethylenedioxy)-cholesta-5,7-diene 
• 16826-35-0 cholesta-4,7-dien-3-one 

Downstream Products

• 1262676-25-4 (3S,5S)-3-Hydroxy-7-oxa-8-cholesten-6-one 
• 1262677-25-7 (3R,5S)-3-hydroxy-7-oxa-8-cholesten-6-one 
• 1262677-35-9 (1S,2R)-2-methyl-2-[(1R,3aR,5R,7aR)-7a-methyl-1-[(R)-6-methylheptan-2-yl]-4-oxooctahydro-1H-inden-5-yl]-5-oxocyclohexanecarboxylic acid 

Relevant articles and documents

3β-Hydroxy-5β-cholest-7-en-6-one as an Intermediate of 20-Hydroxyecdysone Biosynthesis in a Hairy Root Culture of Ajuga reptans var. atropurpurea

-, - and -Cholesterols and - and -3β-hydroxy-5β-cholest-7-en-6-ones were converted with a hairy root culture of Ajuga reptans var. atropurpurea into 20-hydroxyecdysone, in which the deuterium atoms retained their original positions, thus strongly suggesting that 3β-hydroxy-5β-cholest-7-en-6-one is an obligatory intermediate in the biosynthesis of ecdysteroids in the plant.

Synthesis of potential inhibitors of the biosynthesis of ecdysone, the moulting hormone of insects

We have synthesized new potential acetylenic inhibitors of the last step in the biosynthesis of ecdysone, the moulting hormone of insects.The key step in our synthesis is the introduction of the A/B cis ring junction (5β-H configuration) by regio- and stereoselective hydroboration of the Δ5 double bond (B-ring) of 7-dehydrocholesterol. - Keywords: ecdysteroid / ecdysteroid inhibitors / hydroboration / acetylenic derivatives