255050-97-6

Basic information

• Product Name: 4-(2-Acetamidophenyl)-piperidine hydrochloride
• CAS NO: 255050-97-6
• Molecular Weight: 254.76
• Mol File: 255050-97-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(2-Acetamidophenyl)-piperidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Acetamidophenyl)-piperidine hydrochloride(255050-97-6)
• EPA Substance Registry System: 4-(2-Acetamidophenyl)-piperidine hydrochloride(255050-97-6)

Safety Data

• Hazardous Substances Data: 255050-97-6(Hazardous Substances Data)

Usage

Chemical compound

4-(2-Acetamidophenyl)-piperidine hydrochloride

Structure

Consists of a piperidine ring with an acetamidophenyl group attached

Use

Intermediate in the synthesis of pharmaceutical drugs and organic compounds

Salt form

Hydrochloride for increased solubility and stability in aqueous solutions

Applications

Medicinal chemistry and drug development

Value

Building block for new compounds with therapeutic potential

Handling

Care and proper safety protocols required due to potential hazards and risks

Upstream product

• 255050-96-5 4-(2-Acetamidophenyl)-N-Boc-piperidine 

Downstream Products

• 255049-49-1 N-[2-(S)-(3,4-Dichlorophenyl)-4-(4-[2-acetamidophenyl]-1-piperidinyl)butyl]-N-methyl-3-cyano-1-naphthamide Citrate 

Relevant articles and documents

N-SUBSTITUTED NAPHTHALENE CARBOXAMIDES AS NEUROKININ-RECEPTOR ANTAGONISTS

A compound of formula I wherein: R is alkyl; R1 is optionally substituted phenyl 2-oxo-tetrahydro-1(2H)-pyrimidinyl, or 2-oxo-1-piperidinyl; R2 is hydrogen, alkoxy, alkanoyloxy, alkoxycarbonyl, alkanoylamino, acyl, alkyl, carbamoyl, N-alkylcarbamoyl, N,N-dialkylcarbamoyl where the alkyl groups are the same or different, hydroxy, thioacyl, thiocarbamoyl, N-alkylthiocarbamoyl, or N,N-dialkylthiocarbamoyl where the alkyl groups are the same or different. X1 and X2 are independently hydrogen or halo, provided that at least one of X1 or X2 is halo; and R3, R4, R5 and R6 are independently hydrogen, cyano, nitro, trifluoromethoxy, trifluoromethyl, or alkylsulfonyl are antagonists of at least one tachykinin receptor and are useful in the treatment of depression, anxiety, asthma, pain, inflammation, urinary incontinence and other disease conditions. Process for their preparation are described, as are compositions containing them and their use.