25518-22-3Relevant articles and documents
A convenient and general synthesis of trans-3-hydroxyflavanones from chalcones by dimethyldioxirane epoxidation and subsequent base-catalyzed cyclization
Patonay,Toth,Adam
, p. 5055 - 5058 (1993)
2'-Hydroxychalcone epoxides were found to give trans-3-hydroxyflavanone and 2-(α-hydroxybenzyl)-3-coumaranone under basic conditions. Epoxidation of 2'-hydroxychalcones with dimethyldioxirane followed by treatment of tetrabutylammonium hydroxide provides a convenient and general method for the synthesis of trans-3-hydroxyflavanones.