25552-17-4

Basic information

• Product Name: 1-Phenyl-5-methyl-1-hexanone
• Synonyms: 1-Phenyl-5-methyl-1-hexanone;5-Methyl-1-phenyl-1-hexanone
• CAS NO: 25552-17-4
• Molecular Formula: C₁₃H₁₈O
• Molecular Weight: 190.28
• Mol File: 25552-17-4.mol
• Article Data: 23

Chemical Properties

• Boiling Point: 148-151 °C(Press: 17 Torr)
• Appearance: /
• Density: 0.933±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-Phenyl-5-methyl-1-hexanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Phenyl-5-methyl-1-hexanone(25552-17-4)
• EPA Substance Registry System: 1-Phenyl-5-methyl-1-hexanone(25552-17-4)

Safety Data

• Hazardous Substances Data: 25552-17-4(Hazardous Substances Data)

Upstream product

• 5699-78-5 5-methylhexanoyl chloride 
• 71-43-2 benzene 
• 37563-31-8 5-methyl-1-phenyl-hexan-1-ol 
• 147295-86-1 [1-(3-methylbutoxy)ethenyl]benzene 
• 98-86-2 acetophenone 
• 556-82-1 3-methyl-2-buten-1-ol 
• 936-59-4 3-chloropropiophenone 
• 83348-19-0 diethyl 4-isobutyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate 
• 100-52-7 benzaldehyde 
• 7429-94-9 isohexylmagnesium bromide 
• 646-07-1 4-Methylpentanoic acid 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 123-51-3 i-Amyl alcohol 
• 98-85-1 1-Phenylethanol 

Downstream Products

• 26307-39-1 5-Methyl-2-(4-methyl-benzyl)-1-phenyl-hexan-1-one 
• 1436413-30-7 C₂₀H₂₁N 
• 169601-60-9 5,6-dihydro-4-hydroxy-6-(4-methylpentyl)-6-phenyl-2H-pyran-2-one 
• 26307-36-8 2-Benzyl-5-methyl-1-phenyl-hexan-1-on 
• 17697-65-3 (5-methyl-hexyl)-benzene 

Relevant articles and documents

-

-

Mn-Enabled Radical-Based Alkyl-Alkyl Cross-Coupling Reaction from 4-Alkyl-1,4-dihydropyridines

Highly efficient alkylation of β-chloro ketones and their derivatives was achieved by means of domino dehydrochlorination/Mn-enabled radical-based alkyl-alkyl cross-coupling reaction. In situ-generated α,β-unsaturated ketones and their analogues were identified as the reaction intermediates. Known bioactive compounds, such as melperone and azaperone, could be easily prepared from β-chloropropiophenone in two steps.

Photoredox-Catalyzed Decarboxylative Alkylation of Silyl Enol Ethers to Synthesize Functionalized Aryl Alkyl Ketones

Photoredox-catalyzed decarboxylative alkylation of silyl enol ethers has been developed. Diverse functionalized aryl alkyl ketones were afforded in modest to good yields using N-(acyloxy)phthalimide as an easy access alkyl radical source under mild and operationally simple conditions. The excellent performance of drug molecules such as fenbufen and indomethacin and naturally occurring carboxylic acids such as stearic acid and dehydrocholic acid further demonstrated the practicability of the reaction.