255837-19-5 Usage
Description
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL is a white crystalline powder with unique chemical properties that make it suitable for various applications in different industries.
Uses
Used in Chemical Synthesis:
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL is used as a ligand for the palladium-catalyzed monoarylation of malonate esters, 1,3-diketones, and isolated nitroalkanes. Its unique chemical structure allows for efficient and selective reactions, making it a valuable component in the synthesis of various organic compounds.
Used in Suzuki Reaction:
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL is also used in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds, particularly in the synthesis of biaryl compounds. Its role in this reaction contributes to the development of new materials and pharmaceuticals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL is used as a key intermediate in the synthesis of various drugs and drug candidates. Its unique properties enable the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Material Science:
2-(DI-T-BUTYLPHOSPHINO)-2'-METHYLBIPHENYL is utilized in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity. Its application in material science can lead to the creation of advanced materials for various industries, including electronics, automotive, and aerospace.
Check Digit Verification of cas no
The CAS Registry Mumber 255837-19-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,5,8,3 and 7 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 255837-19:
(8*2)+(7*5)+(6*5)+(5*8)+(4*3)+(3*7)+(2*1)+(1*9)=165
165 % 10 = 5
So 255837-19-5 is a valid CAS Registry Number.
255837-19-5Relevant articles and documents
Synthesis of di-tert-butylphenol [...] biphenyl compounds (by machine translation)
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Paragraph 0014, (2019/03/06)
The invention discloses a method for synthesizing tert-[...] biphenyl compounds, which belongs to the field of organic synthesis. In the oxygen free atmosphere, in order to di-tert-butylphenol [...] as raw material, under the action of the palladium catalyst, with the O-bromophenylacetic reaction, then the obtained by coupling with aryl boric acid di-tert-butylphenol [...] biphenyl compound. Compared with the prior art the invention less reaction steps, the operation is simple, high yield, is more suitable for industrial production. (by machine translation)
Highly active and selective catalysts for the formation of α-aryl ketones
Fox, Joseph M.,Huang, Xiaohua,Chieffi, Andre,Buchwald, Stephen L.
, p. 1360 - 1370 (2007/10/03)
Bulky, electron-rich phosphine ligands with a biphenyl backbone, when combined with Pd(OAc)2, give highly active catalysts for the α-arylation of ketones. The ligand 2-methyl-2'-dicyclohexylphosphinobiphenyl is particularly effective, and with
