255882-72-5Relevant articles and documents
2-AZETIDINYL-4-(lH-PYRAZOL-3-YLAMINO)PYRIMIDINES AS INHIBITORS OF INSULIN-LIKE GROWTH FACTOR-I RECEPTOR ACTIVITY
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, (2010/11/24)
A compound of formula (I): wherein the substituents are as defined in the text for use in inhibiting insulin-like growth factor 1 receptor activity in a warm blooded animal such as man.
Preparation comprising an enzyme for asymmetrical hydrolysis of N-substituted C3-C4 cyclic imino-2-carboxylic acid ester and method of using the same
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, (2008/06/13)
There is disclosed an enzyme preparation comprising: (i) a styrene-divinylbenzene copolymer having fine pores with an average radius of 200 - 500?, and (ii) an enzyme capable of asymmetrically hydrolyzing N-substituted C3-C4 cyclic imino-2-carboxylic acid ester to preferentially produce an (S)-N-substituted C3-C4 cyclic imino-2-carboxylic acid, wherein said enzyme comprises an amino acid sequence as set forth in SEQ ID NO: 1 or the like.
Cathepsin cysteine protease inhibitors
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Page 19, (2010/02/06)
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of Cathepsins K and L. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.