25594-62-1 Usage
Description
2-Acetylquinoxaline is an organic compound with the molecular formula C9H8N2O. It is a derivative of quinoxaline, which is a fused bicyclic compound consisting of a benzene ring and a pyrazine ring. 2-Acetylquinoxaline is characterized by the presence of an acetyl group (-COCH3) attached to the second carbon of the quinoxaline structure. 2-ACETYLQUINOXALINE is known for its various applications in different industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
2-Acetylquinoxaline is used as an intermediate in the synthesis of various pharmaceutical compounds. It plays a crucial role in the development of drugs with diverse therapeutic applications, such as antibiotics, anti-inflammatory agents, and anti-cancer drugs. Its presence in the molecular structure of these drugs contributes to their biological activity and efficacy.
Used in Dye Industry:
2-Acetylquinoxaline is also utilized in the dye industry for the production of various types of dyes. Its chemical structure allows it to form stable complexes with different substrates, making it a valuable component in the creation of dyes with specific color properties and stability.
Used in Antibiotic Production:
In the field of antibiotics, 2-Acetylquinoxaline is used in the synthesis of several antibiotics, such as olaquindox, carbadox, echinomycin, levomycin, and actinoleutin. These antibiotics are widely used in the treatment of bacterial infections in both humans and animals.
Used in the Synthesis of Amiloride:
2-Acetylquinoxaline is also employed in the production of amiloride, a medication used to treat high blood pressure and congestive heart failure. Amiloride is a potassium-sparing diuretic that helps regulate the balance of electrolytes in the body, thus contributing to the management of these medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 25594-62-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,5,9 and 4 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 25594-62:
(7*2)+(6*5)+(5*5)+(4*9)+(3*4)+(2*6)+(1*2)=131
131 % 10 = 1
So 25594-62-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H8N2O/c1-7(13)10-6-11-8-4-2-3-5-9(8)12-10/h2-6H,1H3
25594-62-1Relevant articles and documents
Highly chemoselective deoxygenation of N-heterocyclic: N -oxides under transition metal-free conditions
Kim, Se Hyun,An, Ju Hyeon,Lee, Jun Hee
supporting information, p. 3735 - 3742 (2021/05/04)
Because their site-selective C-H functionalizations are now considered one of the most useful tools for synthesizing various N-heterocyclic compounds, the highly chemoselective deoxygenation of densely functionalized N-heterocyclic N-oxides has received much attention from the synthetic chemistry community. Here, we provide a protocol for the highly chemoselective deoxygenation of various functionalized N-oxides under visible light-mediated photoredox conditions with Na2-eosin Y as an organophotocatalyst. Mechanistic studies imply that the excited state of the organophotocatalyst is reductively quenched by Hantzsch esters. This operationally simple technique tolerates a wide range of functional groups and allows high-yield, multigram-scale deoxygenation. This journal is
Nickel-catalyzed electrochemical Minisci acylation of aromatic N-heterocycles with α-keto acids via ligand-to-metal electron transfer pathway
Ding, Hang,Xu, Kun,Zeng, Cheng-Chu
, p. 38 - 43 (2019/11/14)
A nickel-catalyzed electrochemical methodology for the Minisci acylation of aromatic electron-deficient heterocycles with α-keto acids has been developed. The reaction is performed in an undivided cell under constant current conditions, featuring broad scope of substrates and avoiding the conventional utilization of silver-based catalysts in conjunction with excess amount of oxidants. Cyclic voltammetric analysis disclosed that a ligand-to-metal electron transfer process may be involved in the generation of the key acyl radicals.
Iron-Catalyzed Minisci Type Acetylation of N-Heteroarenes Mediated by CH(OEt)3/TBHP
Srinivasulu,Shantharjun,Vani,Ashalu, K. Chinna,Mohd,Wencel-Delord,Colobert,Reddy, K. Rajender
supporting information, p. 1815 - 1819 (2019/02/20)
Iron-catalyzed acetylation of electron deficient N-heteroarenes has been reported using triethylorthoformate as robust and inexpensive acetyl source. This new method is successfully applied for the acetylation of quinolines, isoquinoline, quinoxalines, arylpyridines, bipyridines, and benzothiazole.