25627-20-7

Basic information

• Product Name: [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-
• Synonyms: mesitylaniline;2,6-DIHYDRO-2,2,4-TRIMETHYL-6-QUINOLONE;2'-Amino-2,4,6-trimethylbiphenyl;2',4',6'-trimethyl-biphenyl-2-ylamine;2'-Amino-2,4,6-trimethyl-biphenyl
• CAS NO: 25627-20-7
• Molecular Formula: C15H17N
• Molecular Weight: 211.307
• Mol File: 25627-20-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 314.9±11.0 °C(Predicted)
• Density: 1.026±0.06 g/cm3(Predicted)
• CAS DataBase Reference: [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-(25627-20-7)
• EPA Substance Registry System: [1,1'-Biphenyl]-2-amine, 2',4',6'-trimethyl-(25627-20-7)

Safety Data

• Hazardous Substances Data: 25627-20-7(Hazardous Substances Data)

Usage

Description

[1,1'-Biphenyl]-2-amine, 2',4',6'-trimethylis a chemical compound that belongs to the class of biphenyl amines. It is a derivative of biphenyl, which consists of two benzene rings linked by a single bond. The amine group is located on the 2-position of the biphenyl structure, and there are three methyl groups attached to the 2', 4', and 6' positions of the amine. This unique structure and functional groups make it a valuable building block in the production of complex organic molecules and materials.

Uses

Used in Pharmaceutical Industry:
[1,1'-Biphenyl]-2-amine, 2',4',6'-trimethylis used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique structure allows for the development of new drugs with specific therapeutic properties.
Used in Research:
[1,1'-Biphenyl]-2-amine, 2',4',6'-trimethylis used as a research compound for [application reason], such as studying its chemical properties, reactivity, and potential applications in various fields.
Used in Organic Synthesis:
[1,1'-Biphenyl]-2-amine, 2',4',6'-trimethylis used as a building block in organic synthesis for [application reason], enabling the creation of complex organic molecules and materials with specific properties and functions.

Upstream product

• 694-80-4 2-bromo-1-chlorobenzene 
• 5980-97-2 mesitylboronic acid 
• 615-36-1 2-bromoaniline 
• 1493-13-6 trifluorormethanesulfonic acid 
• 65753-85-7 2-azido-2',4',6'-trimethylbiphenyl 
• 14872-62-9 2,4,6-trimethyl-2'-nitro-1,1'-biphenyl 

Downstream Products

• 204062-60-2 2-methyl-8-(2,4,6-trimethyl-phenyl)-quinolin-4-ol 
• 62533-00-0 2'.4'.6'-Trimethyl-biphenyl-2-sulfonylchlorid 
• 204062-61-3 4-chloro-2-methyl-8-(2,4,6-trimethyl-phenyl)-quinoline 

Relevant articles and documents

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Molybdenum monoaryloxide pyrrolide alkylidene complexes that contain mono-ortho-substituted phenyl imido ligands

Monaryloxide pyrrolide (MAP) molybdenum imido alkylidene complexes of the type Mo(NArX)(CHCMe2R)(Me2Pyr)(OR′) (Me2Pyr = 2,5-dimethylpyrrolide) have been prepared in which NAr X is an ortho-substituted phenylimido group (X = Cl (NAr Cl), CF3 (NArCF3), i-Pr (NAriPr), t-Bu (NArtBu), mesityl (NArM), or TRIP (TRIP = triisopropylphenyl; NArT)) and OR′ = O-2,3,5,6-(C 6H5)4C6H (OTPP), O-2,6-(2,4,6-Me3C6H2)2C 6H3 (OHMT), or O-2,6-(2,4,6-i-Pr3C 6H2)2C6H3 (OHIPT). The object was to explore to what extent relatively "large" NAr M or NArT ligands would alter the performance of MAP catalysts in reactions that have been proposed to depend upon the relative size of the imido and OR′ groups. Preliminary studies employing the ring-opening metathesis polymerization of 5,6-dicarbomethoxynorbornadiene as a measure of selectivity suggest that a single phenylimido ortho substituent, even in an NArM or NArT group, does not produce any unique behavior and that the outcome of the ROMP reaction correlates with the overall relative size of the imido and OR′ group. Single-crystal X-ray structures of six species that contain the new NArM or NArT groups are reported.

INTER- AND INTRA-MOLECULAR AROMATIC N-SUBSTITUTION BY ARYLNITRENIUM-ALUMINIUM CHLORIDE COMPLEXES GENERATED FROM ARYL AZIDES IN THE PRESENCE OF ALUMINIUM CHLORIDE

Reactions of phenyl azide with aromatic compounds ( i. e. benzene, toluene, ethylbenzene, cumene, anisole, and bromobenzene ) in the presence of AlCl3 gave diarylamines, whwreas those of phenyl azides with an electron-donating group such as Me and OMe yield little of the corresponding diarylamines ( tarformation takes place ).The reaction of 4-nitrophenyl azide with benzene in the presence of AlCl3 gave 4-nitrophenyl(phenyl)amine and a C-substitution product, 2-amino-5-nitrobiphenyl.Decomposition of 2-azidophenyl(phenyl)methane and 2-azidobiphenyls in CH2Cl2 in the presence of AlCl3 underwent an N-cyclization to afford 9,10-dihydroacridine and carbazoles, respectively, in good yields.The kinetic data on the decomposition of aryl azides and a Hammet plot ( with p= -6.0 ) for the formation of diarylamines suggest that the products are formed by an aromatic N-substitution of arylnitrenium-AlCl3 complexes via azide-AlCl3 complexes.We further argue the character of arylnitrenium-AlCl3 complexes.