256382-50-0

Basic information

• Product Name: (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone
• Synonyms: (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone;(R)-4-Phenyl-3-(propa-1,2-dienyl)oxazolidin-2-one
• CAS NO: 256382-50-0
• Molecular Formula: C₁₂H₁₁NO₂
• Molecular Weight: 201.22
• Mol File: 256382-50-0.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 309.5°C at 760 mmHg
• Flash Point: 141°C
• Appearance: /
• Density: 1.201g/cm³
• Vapor Pressure: 0.000638mmHg at 25°C
• Refractive Index: 1.621
• PKA: -2.45±0.40(Predicted)
• CAS DataBase Reference: (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone(256382-50-0)
• EPA Substance Registry System: (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone(256382-50-0)

Safety Data

• Hazardous Substances Data: 256382-50-0(Hazardous Substances Data)

Usage

Description

(4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone is an oxazolidinone derivative featuring a four-membered ring with oxygen and nitrogen atoms. This chemical compound is distinguished by its unique structure, which includes a phenyl group and a 1,2-propadienyl group attached to the oxazolidinone ring. (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone's stereochemistry as (4R) may influence its reactivity and biological activity, making it a potentially valuable chemical entity for various applications in organic synthesis and medicinal chemistry.

Uses

Used in Organic Synthesis:
(4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone is used as a building block in organic synthesis for the creation of other complex compounds. Its unique structure and functional groups contribute to the synthesis of a variety of organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone is used as a pharmacophore for drug discovery. Its complex structure and stereochemistry may offer potential in the development of new pharmaceutical agents.
Used in Pharmaceutical Industry:
(4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone is used as a precursor in the pharmaceutical industry for the synthesis of drugs with potential therapeutic applications. Its unique structural features may contribute to the discovery of novel medications.
Used in Research and Development:
(4R)-4-phenyl-3-(1,2-propadienyl)-2-Oxazolidinone is utilized in research and development settings to explore its properties and potential applications. Its reactivity and biological activity are of interest to scientists working on new chemical and pharmaceutical innovations.

InChI:InChI=1/C12H11NO2/c1-2-8-13-11(9-15-12(13)14)10-6-4-3-5-7-10/h3-8,11H,1,9H2/t11-/m0/s1

Upstream product

• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 256382-74-8 (R)-4-phenyl-3-(prop-2-yn-1-yl)oxazolidin-2-one 

Downstream Products

• 606965-07-5 3-{1-[4-(tert-butyl-dimethyl-silanyloxy)-pentyl]-propa-1,2-dienyl}-4-phenyl-oxazolidin-2-one 
• 1029129-84-7 C₁₇H₁₄N₂O₄ 
• 1029129-80-3 C₁₈H₁₇NO₆ 
• 1029129-81-4 C₂₀H₁₉NO₆ 
• 1029129-86-9 C₂₀H₁₉NO₆ 
• 1029129-85-8 C₁₇H₁₇NO₄ 
• 1332480-05-3 C₁₇H₁₇NO₄ 
• 1332480-14-4 C₁₆H₁₄BrNO₄ 
• 1332480-12-2 C₂₂H₁₉NO₄ 
• 1332480-07-5 C₁₉H₁₉NO₆ 
• 1332480-11-1 C₂₂H₂₅NO₆ 
• 1332480-09-7 C₁₉H₁₉NO₆ 

Relevant articles and documents

Efficient preparations of novel ynamides and allenamides

Practical syntheses of a series of novel ynamides and allenamides are described here. While a base-induced isomerization protocol of propargyl amides leads to an array of chiral and achiral allenamides, ynamides are prepared from enamides via bromination followed by base-induced elimination of the Z-bromoenamides. These ynamides and allenamides possess improved thermal stability compared to ynamines and allenamines. They can be isolated, purified, and handled with ease, and thus, should be synthetically more useful than traditional ynamines and allenamines.