2567-59-1

Basic information

• Product Name: N,N-dibutyl-2-chloroacetamide
• Synonyms: Acetamide, N,N-dibutyl-2-chloro-; N,N-Dibutyl-2-chloroacetamide
• CAS NO: 2567-59-1
• Molecular Formula: C₁₀H₂₀ClNO
• Molecular Weight: 205.7249
• Mol File: 2567-59-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 279.1°C at 760 mmHg
• Flash Point: 122.6°C
• Density: 0.982g/cm³
• Vapor Pressure: 0.00409mmHg at 25°C
• Refractive Index: 1.456
• CAS DataBase Reference: N,N-dibutyl-2-chloroacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dibutyl-2-chloroacetamide(2567-59-1)
• EPA Substance Registry System: N,N-dibutyl-2-chloroacetamide(2567-59-1)

Safety Data

• Hazardous Substances Data: 2567-59-1(Hazardous Substances Data)

Usage

General Description

N,N-dibutyl-2-chloroacetamide is a chemical compound with the molecular formula C10H20ClNO. It is an organic compound that belongs to the class of amides and features two butyl chains attached to the nitrogen atom. The presence of the chloro group on the acetamide moiety gives this compound its unique chemical properties. It is commonly used as a chemical intermediate in the synthesis of various pharmaceuticals, agrochemicals, and other organic compounds. N,N-dibutyl-2-chloroacetamide is known for its mild antibacterial properties and is often utilized as a preservative or antimicrobial agent in cosmetic and personal care products. Additionally, it is used as an additive in industrial processes to prevent the growth of bacteria and fungi.

Upstream product

• 111-92-2 dibutylamine 
• 79-04-9 chloroacetyl chloride 
• 4015-58-1 monochloroacetic acid anhydride 
• 22118-09-8 2-bromoacetyl chloride 
• 79-11-8 chloroacetic acid 

Downstream Products

• 145290-28-4 N,N-Dibutyl-2-(di-p-tolyl-phosphinoyl)-acetamide 
• 145290-27-3 N,N-Dibutyl-2-(di-m-tolyl-phosphinoyl)-acetamide 
• 106231-57-6 Benzoic acid dibutylcarbamoylmethyl ester 

Relevant articles and documents

Benzotriazole xanthate derivative lubricant additive and preparation method thereof

The invention discloses a benzotriazole xanthate derivative lubricant additive. According to the invention, the benzotriazole xanthate derivative lubricant additive is prepared according to the following steps: performing amidation on alkylamine and chloroacetyl chloride under the effect of alkali, thereby acquiring alkyl chloroacetamide; performing nucleophilic substitution reaction on benzotriazole, chloropropanol and carbon disulfide, thereby acquiring benzotriazole propyl xanthic sodium or potassium; performing nucleophilic substitution reaction on alkyl chloroacetamide and benzotriazole propyl xanthic sodium or potassium, thereby acquiring a compound with a general formula I. According to the invention, the preparation method is simple, the technical condition is mild, the raw materials are easily acquired, the compounding cost is low and the compounding yield is high. The benzotriazole xanthate derivative can be independently used as an extreme pressure wear-resistant anticorrosion additive of lubricating oil, also can be used together with the other lubricant additives, is capable of obviously promoting the carrying capacity of the base oil, greatly improving the wear-resistant antifriction performance of the base oil and effectively promoting the corrosion resistance of the base oil and is a biodegradable multifunctional lubricant additive.

Synthesis of berberine bromide analogs containing tertiary amides of acetic acid in the 9-O-position

9-O-Acetamide analogs of berberine bromide were prepared in 20-87% yields via reaction of the isoquinoline alkaloid berberrubine with tertiary amides of bromoacetic acid. Aminolysis did not occur during reaction of methyl-2-(9-demethoxyberberine bromide-9-yl)hydroxyacetate with secondary amines. The corresponding acid or its ethyl ester was isolated.

"Crowned" Fe4S4 Clusters as Electrochemical Metal Ion Sensors

A series of Fe4S4 cluster compounds I, III, and V, in which the cuboidal cluster core is appended with four crown ether thiolate ligands, and II and IV, bearing thiolate ligands without crown ether parts, has been synthesized and characterized. The spectroscopic and electrochemical properties of these compounds are determined by the electronic nature of the thiolate ligands. Only in the case of III, where a very short α-thioacetyl linker was used to connect the crown ether ligands to the cluster core, was a restricted conformational freedom of the ligand observed. A detailed electrochemical study of the influence of alkali and earth alkali metal ions (Li+, Na+, K+, Mg2+, and Ba2+) on the reversible 2-/3- reduction of the cluster compounds was performed. In the case of the crown ether appended clusters I,III, and V, the addition of these metal ions resulted in an anodic shift, i.e. in positive direction, of the reduction potential (modulation effect) and to larger current responses (promotion effect). The magnitude of the modulation effects is determined by the binding affinity of the metal ions in the crown ether ligands, and by the distance between bound metal ions and the redox active cluster core. Variation of the linker between the cluster core and the metal ion binding site resulted in cluster compounds with almost inverse selectivities for e.g. K+ and Ba2+ in the case of I and III. For the large effects found for compound I a lariat binding mode is proposed.