25679-24-7

Basic information

• Product Name: H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2
• Synonyms: CCK-8 NON SULFATED;CCK OCTAPEPTIDE, NON-SULFATED;CCK OCTAPEPTIDE (CCK-8), NON-SULFATED;CCK-OCTAPEPTIDE (26-33) AMMONIUM;CCK, OCTAPEPTIDE (26-33), NON-SULFATED FORM;DYMGWMDF-NH2;DESULFATED CCK-8 (26-33);CK-8 UNSULFATED CHOLECYSTOKININ FRAGM
• CAS NO: 25679-24-7
• Molecular Formula: C49H62N10O13S2
• Molecular Weight: 1063.21
• Product Categories: Cholecystokinin (CCK) receptor;peptide
• Mol File: 25679-24-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 1570.2 °C at 760 mmHg
• Flash Point: 903.4 °C
• Appearance: /powder
• Density: 1.387 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.638
• Storage Temp.: −20°C
• PKA: 3.71±0.10(Predicted)
• CAS DataBase Reference: H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2(CAS DataBase Reference)
• NIST Chemistry Reference: H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2(25679-24-7)
• EPA Substance Registry System: H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2(25679-24-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 25679-24-7(Hazardous Substances Data)

Usage

Description

H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2, also known as Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated, is a peptide derived from the larger cholecystokinin molecule. It consists of a sequence of amino acids that play a crucial role in various physiological processes, particularly in the regulation of digestion and appetite.

Uses

Used in Pharmaceutical Industry:
H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2 is used as a pharmacological agent for its role in the regulation of digestion and appetite. It is particularly useful in the development of drugs targeting obesity and related metabolic disorders by modulating satiety and digestion processes.
Used in Research Applications:
In the field of research, H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2 is used as a specific reagent for testing the specificity of various proteins, such as gastrin and pepsinogen I. This application aids in understanding the interactions between these proteins and their potential roles in physiological processes.
Used in Diagnostic Applications:
H-ASP-TYR-MET-GLY-TRP-MET-ASP-PHE-NH2 can also be employed in the development of diagnostic tools and tests to measure the levels of gastrin and pepsinogen I in patients, which may be indicative of certain gastrointestinal disorders or conditions.

Biochem/physiol Actions

Biologically inactive form of CCK-8; CCKB/gastrin receptor agonist that has no activity at the CCKA receptor.

InChI:InChI=1/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)

Relevant articles and documents

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