257298-94-5

Basic information

• Product Name: (R)-pinacol (1-(p-methylphenyl)ethyl) boronate
• Synonyms: (R)-pinacol (1-(p-methylphenyl)ethyl) boronate
• CAS NO: 257298-94-5
• Molecular Weight: 246.157
• Mol File: 257298-94-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-pinacol (1-(p-methylphenyl)ethyl) boronate(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-pinacol (1-(p-methylphenyl)ethyl) boronate(257298-94-5)
• EPA Substance Registry System: (R)-pinacol (1-(p-methylphenyl)ethyl) boronate(257298-94-5)

Safety Data

• Hazardous Substances Data: 257298-94-5(Hazardous Substances Data)

Upstream product

• 622-97-9 1-ethenyl-4-methylbenzene 
• 76-09-5 2,3-dimethyl-2,3-butane diol 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 73183-34-3 bis(pinacol)diborane 

Downstream Products

• 124709-71-3 R-(-)-2-(4'-methylphenyl)-propanoic acid 
• 122091-54-7 (R)-(+)-2-(4-methylphenyl)propanol 
• 42070-92-8 (R)-1-(4-methylphenyl)ethanol 

Relevant articles and documents

Nickel-Catalyzed Enantioselective Hydroboration of Vinylarenes

The enantioselective hydroboration of vinylarenes catalyzed by a chiral, nonracemic nickel catalyst is presented as a facile method for generating chiral benzylic boronate esters. Various vinylarenes react with bis(pinacolato)diboron (B2pin2) in the presence of MeOH as a hydride source to form chiral boronate esters in up to 92% yield with up to 94% ee. The use of anhydrous Me4NF to activate B2pin2 is crucial for ensuring fast transmetalation to achieve high enantioselectivities.

Cross coupling reactions of chiral secondary organoboronic esters with retention of configuration

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