257299-95-9

Basic information

• Product Name: [(1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-methanol
• Synonyms: [(1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-methanol
• CAS NO: 257299-95-9
• Molecular Weight: 517.385
• Mol File: 257299-95-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [(1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [(1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-methanol(257299-95-9)
• EPA Substance Registry System: [(1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-yl]-methanol(257299-95-9)

Safety Data

• Hazardous Substances Data: 257299-95-9(Hazardous Substances Data)

Upstream product

• 257300-03-1 (1R,3S)-6,8-Dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-3-triisopropylsilanyloxymethyl-1,2,3,4-tetrahydro-isoquinoline 
• 257300-01-9 2-[1-(tert-butyl-dimethyl-silanyloxymethyl)-2-(3,5-dimethoxy-phenyl)-ethyl]-isoindole-1,3-dione 
• 257299-93-7 (1R,3S)-6,8-Dimethoxy-1-methyl-3-triisopropylsilanyloxymethyl-1,2,3,4-tetrahydro-isoquinoline 
• 257299-91-5 3-(tert-butyl-dimethyl-silanyloxymethyl)-6,8-dimethoxy-1-methyl-3,4-dihydro-isoquinoline 
• 257300-02-0 N-[2-(tert-butyl-dimethyl-silanyloxy)-1-(3,5-dimethoxy-benzyl)-ethyl]-acetamide 
• 257299-90-4 1-(tert-butyl-dimethyl-silanyloxy)-3-(3,5-dimethoxy-phenyl)-propan-2-ol 
• 257299-92-6 ((1R,3S)-6,8-Dimethoxy-1-methyl-1,2,3,4-tetrahydro-isoquinolin-3-yl)-methanol 
• 228704-10-7 2-(tert-butyl-dimethyl-silanyloxy)-1-(3,5-dimethoxy-benzyl)-ethylamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 257299-94-8 (1R,3S)-5-Iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-3-triisopropylsilanyloxymethyl-1,2,3,4-tetrahydro-isoquinoline 

Downstream Products

• 1248682-79-2 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 1-naphthoate 
• 1248682-73-6 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 4-octylbenzoate 
• 1248682-75-8 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 2-(3,5-dimethoxyphenyl)acetate 
• 1248682-78-1 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 2-(3,5-di-tert-butylphenyl)acetate 
• 1248682-62-3 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl acetate 
• 1248682-70-3 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 3,5-dimethoxybenzoate 
• 1248682-80-5 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 2-naphthoate 
• 1248682-72-5 ((1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-tosyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl 3,5-di-tert-butylbenzoate 
• 257300-00-8 2-Diphenylphosphanyl-benzoic acid (1R,3S)-5-iodo-6,8-dimethoxy-1-methyl-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-isoquinolin-3-ylmethyl ester 

Relevant articles and documents

A stereospecific, intermolecular biaryl-coupling approach to korupensamine A en route to the michellamines

By what means and how well can axial chirality be controlled in an intermolecular Suzuki biaryl cross-coupling reaction? The directionality of reductive elimination [Eq.(1)] is completely controlled by using a strategically positioned internal ligand L to afford a single biaryl atropisomer corresponding to the korupensamine A skeleton. TIPS = iPr3Si, Ts = H3CC6H4SO2.