25755-93-5Relevant articles and documents
Mechanistic understanding of a silver pyridylpyrrolide as a catalyst for 3 + 2 cyclization of a nitrile with diazo ester
Flores, Jaime A.,Pal, Kuntal,Carroll, Maria E.,Pink, Maren,Karty, Jonathan A.,Mindiola, Daniel J.,Caulton, Kenneth G.
, p. 1544 - 1552 (2014)
The trinuclear argentate complex Ag3(μ2-3,5- (CF3)2PyrPy)3 (PyrPy = 2,2′- pyridylpyrrolide) catalyzes the 3 + 2 cycloaddition of several NCR (R = Me, Ph, tBu) and N2CHCO2Et to disubstituted oxazoles, even in the presence of light and air. Structural and theoretical studies imply a three-coordinate silver carbene complex, (3,5-(CF3) 2PyrPy)Ag(CHCO2Et), to be responsible in a stepwise nitrile addition and cyclization step to form the heterocycle.
Copper-Catalyzed Aerobic Oxidative [2 + 3] Cyclization/Aromatization Cascade Reaction: Atom-Economical Access to Tetrasubstituted 4,5-Biscarbonyl Imidazoles
Xie, Jialin,Huang, Yuanqiong,Song, Hongjian,Liu, Yuxiu,Wang, Qingmin
, p. 6056 - 6059 (2017/11/27)
An atom-economical method for accessing tetrasubstituted 4,5-biscarbonylimidazoles by reaction between glycine derivatives and 5-alkoxyoxazoles is reported. The method, which involves a copper-catalyzed aerobic oxidative [2 + 3] cyclization/aromatization
Synthesis and reactivity of 4-silylated oxazoles
Ducept, Pascal C.,Marsden, Stephen P.
, p. 692 - 294 (2007/10/03)
Treatment of (triethylsilyl)diazoacetates with rhodium(II) octanoate and a range of substituted nitriles generates trisubstituted oxazoles bearing a triethylsilyl group in the 4-position. Fluoride-mediated desilylation yields 3,5-disubstituted oxazoles, w
