25774-60-1

Basic information

• Product Name: phenyl phenoxyacetate
• Synonyms: phenyl phenoxyacetate
• CAS NO: 25774-60-1
• Molecular Formula: C₁₄H₁₂O₃
• Molecular Weight: 228.24328
• Mol File: 25774-60-1.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: phenyl phenoxyacetate(CAS DataBase Reference)
• NIST Chemistry Reference: phenyl phenoxyacetate(25774-60-1)
• EPA Substance Registry System: phenyl phenoxyacetate(25774-60-1)

Safety Data

• Hazardous Substances Data: 25774-60-1(Hazardous Substances Data)

Upstream product

• 701-99-5 Phenoxyacetyl chloride 
• 78-93-3 butanone 
• 122-59-8 2-phenoxyacetic acid 
• 620-73-5 phenyl chloroacetate 
• 108-95-2 phenol 
• 999-75-7 ethylzinc iodide 
• 139-02-6 sodium phenoxide 

Downstream Products

• 73014-19-4 1-(2,4-dihydroxyphenyl)-2-phenoxyethan-1-one 
• 431891-29-1 (4-bromo-phenoxy)-acetic acid phenyl ester 
• 621-88-5 phenoxyacetamide 
• 2555-49-9 phenoxyacetic acid ethyl ester 
• 107940-17-0 1,2-Diphenoxy-1-(trimethylsiloxy)ethen 
• 18705-01-6 2-phenoxy-N-phenylacetamide 

Relevant articles and documents

Electron-withdrawing substituents decrease the electrophilicity of the carbonyl carbon. An investigation with the aid of 13C NMR chemical shifts, v(C=O) frequency values, charge densities, and isodesmic reactions to interprete substituent effects on reactivity

13C NMR chemical shifts and v(C=O) frequencies have been measured for several series of phenyl-or acyl-substituted phenyl acetates and for acyl-substituted methyl acetates to investigate the substituent-induced changes in the electrophilic character of the carbonyl carbon. Charge density, bond order, and energy calculations have also been performed. The spectroscopic and charge density results indicate that opposite to the conventional thinking, electron-withdrawing substituents do not increase the electrophilicity of the carbonyl carbon but instead decrease it. On the other hand, reaction energies of the isodesmic reactions designed show that electron-withdrawing substituents destabilize the carbonyl derivatives investigated. So, a significant ground-state destabilization of carboxylic acid esters, and carbonyl compounds in general, due to the decreased resonance stabilization, is proposed as a novel concept to explain both the increase in their reactivity and the changes in the chemical shifts and carbonyl frequencies induced by electron-withdrawing substituents.

SYNTHESIS OF REPELLENTS, PHENOXYACETIC ACID DERIVATIVES.

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