258502-85-1

Basic information

• Product Name: N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]quinoline-6-carboxamide
• Synonyms: N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]quinoline-6-carboxamide
• CAS NO: 258502-85-1
• Molecular Weight: 424.502
• Mol File: 258502-85-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]quinoline-6-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]quinoline-6-carboxamide(258502-85-1)
• EPA Substance Registry System: N-[5-(3-dimethylaminobenzamido)-2-methylphenyl]quinoline-6-carboxamide(258502-85-1)

Safety Data

• Hazardous Substances Data: 258502-85-1(Hazardous Substances Data)

Upstream product

• 258503-83-2 N-(5-amino2-methylphenyl)quinoline-6-carboxamide 
• 200731-31-3 HATU 
• 215309-00-5 3-(4-morpholinyl)benzoic acid 
• 10349-57-2 Quinoline-6-carboxylic acid 
• 107-83-5 2-Methylpentane 
• 221876-01-3 N-(3-amino-4-methylphenyl)-3-dimethylaminobenzamide 

Relevant articles and documents

Amide derivatives useful as inhibitors of the production of cytokines

The invention concerns amide derivatives of formula (I) wherein R3is (1-6C)alkyl or halogeno; Q1is heteroaryl which is optionally substituted with 1, 2, 3, or 4 substituents such as hydroxy, halogeno, trifluoromethyl, (1-6C)alkyl, (1-6C)alkoxy, hydroxy-(1-6C)alkyl, (1-6C)alkoxy-(1-6C)alkyl, hydroxy-(2-6C)alkoxy, amino-(2-6C)alkylamino, N-(1-6C)alkyl-(1-6C)alkylamino-(2-6C)alkylamino, aryl, heteroaryl and heterocyclyl; p is 0-2 and R2is a substituent such as hydroxy and halogeno; q is 0-4; and Q2includes optionally substituted aryl, cycloalkyl, heteroaryl and heterocyclyl; or pharmaceutically-acceptable salts or in vivo-cleavable esters thereof; processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or medical conditions mediated by cytokines.