258818-34-7

Basic information

• Product Name: Larazotide
• Synonyms: larazotide;Glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolylglycine;Unii-zn3R5560zv;Gly-Gly-Val-Leu-Val-Gln-Pro-Gly
• CAS NO: 258818-34-7
• Molecular Formula: C32H55N9O10
• Molecular Weight: 725.83
• Mol File: 258818-34-7.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Density: 1.254
• CAS DataBase Reference: Larazotide(CAS DataBase Reference)
• NIST Chemistry Reference: Larazotide(258818-34-7)
• EPA Substance Registry System: Larazotide(258818-34-7)

Safety Data

• Hazardous Substances Data: 258818-34-7(Hazardous Substances Data)

Usage

General Description

Larazotide acetate, also known as AT-1001, is a synthetic peptide that acts as a tight junction modulator to improve epithelial barrier function in the intestine. It works by blocking the action of zonulin, a protein that regulates the permeability of tight junctions between intestinal epithelial cells. By inhibiting zonulin, Larazotide helps to prevent the passage of harmful substances, such as bacteria and toxins, across the intestinal barrier, potentially reducing inflammation and other symptoms associated with conditions like celiac disease and irritable bowel syndrome. Clinical trials have shown promising results for the use of Larazotide as a treatment for these and other gastrointestinal disorders.