258827-11-1Relevant articles and documents
Synthesis and biological evaluation of 1-azabicyclo-[3.2.1]octanes: New dopamine transporter inhibitors
Tamiz, Amir P.,Smith, Miles P.,Enyedy, Istvan,Flippen-Anderson, Judith,Zhang, Mei,Johnson, Kenneth M.,Kozikowski, Alan P.
, p. 1681 - 1686 (2000)
The synthesis and biological activity of a series of 6-substituted 1-azabicyclo[3.2.1]octanes are described. 1-Azabicyclo[3.2.1]octanes represent a new class of compounds that exhibit monoamine transporter inhibitory activity highly dependent on the overall topology and the absolute stereochemistry of the molecule. (C) 2000 Elsevier Science Ltd. All rights reserved.