258857-76-0Relevant articles and documents
2-Phenylquinoline-carbohydrate hybrids: Molecular design, chemical synthesis, and evaluation of a new family of light-activatable DNA-cleaving agents
Toshima, Kazunobu,Takano, Ryusuke,Maeda, Yutaka,Suzuki, Masataka,Asai, Akira,Matsumura, Shuichi
, p. 3733 - 3735 (1999)
Artificial intercalator-carbohydrate hybrids such as that shown in the scheme cleave DNA at the site of guanine on irradiation with UV light with a long wavelength. The hybrids also exhibit strong cytotoxicity when irradiated. The hybrid system is very im