25948-15-6

Basic information

• Product Name: 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol
• Synonyms: 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol;Ethanol, 2-[methyl(5-nitro-2-pyridinyl)amino]- (9CI);2-[Methyl(5-nitro-2-pyridinyl)amino]ethanol
• CAS NO: 25948-15-6
• Molecular Formula: C₈H₁₁N₃O₃
• Molecular Weight: 197.19124
• EINECS: 247-359-1
• Product Categories: PYRIDINE
• Mol File: 25948-15-6.mol
• Article Data: 8

Chemical Properties

• Melting Point: 86.5-87.5 °C
• Boiling Point: 386.4°Cat760mmHg
• Flash Point: 187.5°C
• Appearance: /
• Density: 1.345g/cm³
• Vapor Pressure: 1.16E-06mmHg at 25°C
• Refractive Index: 1.618
• PKA: 14.47±0.10(Predicted)
• CAS DataBase Reference: 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol(25948-15-6)
• EPA Substance Registry System: 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol(25948-15-6)

Safety Data

• Hazardous Substances Data: 25948-15-6(Hazardous Substances Data)

Usage

Description

2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol is a chemical compound known for its broad-spectrum antibacterial and antifungal properties. It is commonly utilized as an antiseptic and disinfectant agent, disrupting the cell membrane of microorganisms and leading to their destruction.

Uses

Used in Pharmaceutical and Personal Care Products:
2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol is used as an antiseptic and disinfectant agent for its ability to combat a wide range of bacteria and fungi, ensuring the safety and efficacy of pharmaceutical and personal care products.
Used in Industrial Settings:
In the industrial sector, 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol is used as a biocide and preservative for water-based products, preventing the growth of harmful microorganisms and maintaining product integrity.
Used in Treatment of Parasitic Infections:
2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol has potential applications in the treatment of certain parasitic infections, offering a chemical intervention to combat parasitic organisms.
It is crucial to handle 2-[N-methyl-N-(5-nitro-2-pyridyl)amino]ethanol with care due to its potential hazards if not used properly.

InChI:InChI=1/C8H11N3O3/c1-10(4-5-12)8-3-2-7(6-9-8)11(13)14/h2-3,6,12H,4-5H2,1H3

Upstream product

• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 4548-45-2 2-chloro-5-nitropyridine 
• 5418-51-9 5-nitro-2-hydroxypyridine 

Downstream Products

• 4928-46-5 2-((5-aminopyridin-2-yl)(methyl)amino)ethanol 
• 1419603-59-0 phenyl 6-((2-hydroxyethyl)(methyl)amino)pyridin-3-ylcarbamate 
• 1435933-31-5 C₂₀H₂₇N₃O₃ 
• 1435933-41-7 C₂₀H₂₆BrN₃O₃ 
• 1435933-40-6 C₂₄H₃₅N₃O₃ 
• 1435933-39-3 C₂₆H₃₃N₃O₃ 
• 1435933-38-2 C₁₇H₁₈F₃N₃O₃ 
• 1435933-37-1 C₁₉H₂₅N₃O₃ 
• 1435933-36-0 C₁₆H₁₉N₃O₃ 
• 1435933-35-9 C₂₀H₂₇N₃O₃ 
• 1435933-34-8 C₂₀H₂₇N₃O₃ 
• 1419599-68-0 1-((1-(3-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)methyl)-3-(6-((2-hydroxyethyl)(methyl)amino)pyridin-3-yl)urea 

Relevant articles and documents

SUBSTITUTED HETEROCYCLIC AZA DERIVATIVES

The invention relates to heterocyclic aza derivatives as vanilloid receptor ligands, to pharmaceutical compositions containing these compounds and also to these compounds for use in the treatment and/or prophylaxis of pain and further diseases and/or disorders.

Substituted Heterocyclic Aza Compounds

Heterocyclic aza compounds as vanilloid receptor ligands, pharmaceutical compositions containing these compounds and also methods of using these compounds for the treatment and/or inhibition of pain and further diseases and/or disorders.

Discovery of potent transient receptor potential vanilloid 1 antagonists: Design and synthesis of phenoxyacetamide derivatives

We aimed to discover a novel type of transient receptor potential vanilloid 1 (TRPV1) antagonist because such antagonists are possible drug candidates for treating various disorders. We modified the structure of hit compound 7 (human TRPV1 IC50 = 411 nM) and converted its pyrrolidino group to a (hydroxyethyl)methylamino group, which substantially improved inhibitory activity (15d; human TRPV1 IC50 = 33 nM). In addition, 15d ameliorated bladder overactivity in rats in vivo.