25952-74-3 Usage
General Description
3,5-Dibromo-4-hydroxybenzaldehyde oxime is a chemical compound that is commonly used in organic synthesis and research laboratories. It is a derivative of benzaldehyde and contains two bromine atoms at positions 3 and 5, as well as a hydroxyl group at position 4. The oxime functional group consists of the nitrogen atom bonded to the carbon atom of the aldehyde group, forming a stable compound. This chemical has potential applications in the pharmaceutical and agrochemical industries and is often used as a building block for the synthesis of various organic compounds. Additionally, it may also exhibit biological activities and could be of interest for further investigation in medicinal chemistry and drug discovery research.
Check Digit Verification of cas no
The CAS Registry Mumber 25952-74-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,5,9,5 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 25952-74:
(7*2)+(6*5)+(5*9)+(4*5)+(3*2)+(2*7)+(1*4)=133
133 % 10 = 3
So 25952-74-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H5Br2NO2/c8-5-1-4(3-10-12)2-6(9)7(5)11/h1-3,11-12H/b10-3+
25952-74-3Relevant articles and documents
Ruthenium-catalyzed rearrangement of aldoximes to primary amides in water
Garcia-Alvarez, Rocio,Diaz-Alvarez, Alba E.,Borge, Javier,Crochet, Pascale,Cadierno, Victorio
, p. 6482 - 6490 (2012/10/30)
The rearrangement of aldoximes to primary amides has been studied using the readily available arene-ruthenium(II) complex [RuCl2(η 6-C6Me6){P(NMe2)3}] (5 mol %) as catalyst. Reactions proceeded cleanly in pure water at 100 °C without the assistance of any cocatalyst, affording the desired amides in high yields (70-90%) after short reaction times (1-7 h). The process was operative with both aromatic, heteroaromatic, α,β-unsaturated, and aliphatic aldoximes and tolerated several functional groups. Reaction profiles and experiments using 18O-labeled water indicate that two different mechanisms are implicated in these transformations. In both of them, nitrile intermediates are initially formed by dehydration of the aldoximes. These intermediates are then hydrated to the corresponding amides by the action of a second molecule of aldoxime or water. A kinetic analysis of the rearrangement of benzaldoxime to benzamide is also discussed.
