259675-58-6Relevant articles and documents
A mild method for ring-opening aminolysis of lactones
Liu, Wenming,Xu, David D.,Repi?, Oljan,Blacklock, Thomas J.
, p. 2439 - 2441 (2001)
A mild and general method for lactone aminolysis is reported. Sodium 2-ethylhexanoate (NaEH) is found to serve both as a base and a catalyst in aminolysis of a variety of lactones by benzylamine hydrochloride. The nearly neutral pH conditions make this method applicable to many acid/base sensitive substrates.
Facile synthesis of optically active γ-lactones via lipase-catalyzed reaction of 4-substituted 4-hydroxybutyramides
Matsumura, Yasufumi,Endo, Teruko,Chiba, Mitsuo,Fukawa, Hidemichi,Terao, Yoshiyasu
, p. 304 - 305 (2007/10/03)
Lipase-catalyzed transesterification of racemic 4-substituted 4- hydroxybutyramides with succinic anhydride proceeded enantioselectively to afford (S)-succinic acid monoester and unreacted (R)-4-hydroxybutyramide derivative, which were separated easily by