25978-68-1

Basic information

• Product Name: 4-Cyano-3-methylBenzoic acid methyl ester
• Synonyms: 4-Cyano-3-methylBenzoic acid methyl ester;Methyl 4-cyano-3-methylbenzoate
• CAS NO: 25978-68-1
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.186
• Mol File: 25978-68-1.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 311.8 °C at 760 mmHg
• Flash Point: 145.2 °C
• Appearance: /
• Density: 1.15
• Vapor Pressure: 0.000551mmHg at 25°C
• Refractive Index: 1.53
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Cyano-3-methylBenzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Cyano-3-methylBenzoic acid methyl ester(25978-68-1)
• EPA Substance Registry System: 4-Cyano-3-methylBenzoic acid methyl ester(25978-68-1)

Safety Data

• Hazardous Substances Data: 25978-68-1(Hazardous Substances Data)

Usage

General Description

4-Cyano-3-methylBenzoic acid methyl ester, also known as methyl 4-cyano-3-methylbenzoate, is a chemical compound with the formula C10H9NO2. It is a white crystalline powder with a molecular weight of 175.18 g/mol. 4-Cyano-3-methylBenzoic acid methyl ester is commonly used in organic synthesis and pharmaceutical research as a starting material or intermediate. It is also used as a building block in the manufacturing of various pharmaceutical drugs and agrochemicals. Additionally, it may have potential applications in the development of new materials and biologically active compounds. However, as with any chemical compound, proper handling and storage procedures should be followed to ensure safety and prevent any potential hazards.

InChI:InChI=1/C10H9NO2/c1-7-5-8(10(12)13-2)3-4-9(7)6-11/h3-5H,1-2H3

Upstream product

• 557-21-1 dicyanozinc 
• 148547-19-7 4-Bromo-3-methylbenzoic acid methyl ester 
• 557-21-1 zinc(II) cyanide 
• 5471-81-8 methyl 4-iodo-3-methylbenzoate 
• 75-05-8 acetonitrile 
• 18595-14-7 methyl 4-amino-3-methylbenzoate 
• 544-92-3 copper(I) cyanide 
• 67-56-1 methanol 
• 1160759-52-3 4-cyano-3-methylbenzoyl chloride 
• 74-88-4 methyl iodide 

Downstream Products

• 1219018-71-9 4-(2-cyanopropanoyl)-2-methylbenzonitrile 
• 908562-25-4 methyl 3-bromomethyl-4-cyanobenzoate 
• 943917-33-7 methyl 4-carbamothioyl-3-methylbenzoate 
• 503470-27-7 methyl 4-(aminomethyl)-3-methylbenzoate 
• 905308-51-2 4-[5-(4-cyclohexyl-phenyl)-[1,2,4]oxadiazol-3-yl]-3-methyl-benzoic acid methyl ester 
• 905308-44-3 Methyl 4-[(Z)-amino(hydroxyimino)methyl]-3-methylbenzoate 
• 1196047-14-9 methyl 4-(aminomethyl)-3-methylbenzoate hydrochloride 

Relevant articles and documents

-

-

NOVEL FIVE-MEMBERED RING COMPOUND

Disclosed is a five-membered ring compound represented by formula (1) or a pharmaceutically acceptable salt thereof. The compound inhibits infiltration of leukocytes including eosinophils and lymphocytes, and is effective as a drug for treating various inflammations. The compound is highly safe and can be administered for a long period. A pharmaceutical product containing the five-membered ring compound or a pharmaceutically acceptable salt thereof is also disclosed. (In the formula, R1 represents a halogen atom or a phenyl group which may be substituted by a C1-C3 alkyl group or a C1-C3 alkoxy group; R2 represents a C1-C3 alkylene group which may be substituted by a C1-C3 alkyl group or a carbonyl group; R3 represents a C1-C3 alkyl group; R4 and R5 independently represent a hydrogen atom or a C1-C3 alkyl group, or -N(R4)R5 may represent a morpholino group which may be substituted by a C1-C3 alkyl group; Y2 represents a C2-C4 alkylene group; and R6 represents a hydrogen atom, a halogen atom, a C1-C3 alkyl group or a C1-C3 alkoxy group.)

AMIDE COMPOUNDS USEFUL IN THERAPY

A compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof, (I) wherein, R1 and R2 each independently represent H, halogen, CF3, C1-3 alkyl or C1-3 alkoxy; R3 represents C1-6 alkyl, C3-6 cycloalkyl, phenyl (optionally substituted by one or more substituents each independently selected from Ra) or Het (optionally substituted by one or more substituents each independently selected from OH, oxo, or C1-4 alkyl); R4 represents H or C1-3 alkyl; R5 represents C1-6 alkyl (optionally substituted by one or more substituents each independently selected from Rb), C3-6 cycloalkyl (optionally substituted by one or more substituents each independently selected from oxo or OH), or Het2 (optionally substituted by one or more substituents each independently selected from Rd); oxygen atom or 1 sulphur atom, or (c) 1 oxygen atom or 1 sulphur atom, (optionally substituted by one or more substituents each independently selected from OH, oxo or C1-4 alkyl); and R6 represents C1-3 alkyl (optionally substituted by one or more substituents each independently selected from Rf), C3-5 cycloalkyl (optionally substituted by one or more halogen), CN or halogen; where Rf represents halogen or phenyl: and compositions, processes for the preparation, and uses thereof, e.g. in the treatment of endometriosis or uterine fibroids.