259809-74-0

Basic information

• Product Name: 5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate
• Synonyms: 5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate;5-tert-butyl 2-Methyl 4H,5H,6H,7H-[1,3]oxazolo[5,4-c]pyridine-2,5-dicarboxylate;5-tert-butyl 2-ethyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate
• CAS NO: 259809-74-0
• Molecular Formula: C13H18N2O5
• Molecular Weight: 282.29
• Product Categories: CHIRAL CHEMICALS
• Mol File: 259809-74-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 395.6 °C at 760 mmHg
• Flash Point: 193.1 °C
• Appearance: /
• Density: 1.235
• Vapor Pressure: 1.81E-06mmHg at 25°C
• Refractive Index: 1.515
• PKA: -1.61±0.20(Predicted)
• CAS DataBase Reference: 5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate(259809-74-0)
• EPA Substance Registry System: 5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate(259809-74-0)

Safety Data

• Hazardous Substances Data: 259809-74-0(Hazardous Substances Data)

Usage

General Description

5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate is a chemical compound with the molecular formula C16H21NO5. It is a derivative of pyridine and oxazole that contains two carboxylate groups. 5-tert-butyl 2-methyl 6,7-dihydrooxazolo[5,4-c]pyridine-2,5(4H)-dicarboxylate is commonly used in pharmaceutical research and development, as it has potential therapeutic applications due to its ability to interact with biological systems. It has also been studied for its potential use in the treatment of neurological disorders and as a potential analgesic. Additionally, this compound has been investigated for its potential antiviral and antibacterial properties. Its chemical structure and properties make it a valuable and versatile compound for various scientific and medical applications.

InChI:InChI=1/C13H18N2O5/c1-13(2,3)20-12(17)15-6-5-8-9(7-15)19-10(14-8)11(16)18-4/h5-7H2,1-4H3

Upstream product

• 259809-73-9 5-(tert-Butoxycarbonyl)-2-formyl-4,5,6,7-tetrahydro-oxazolo[5,4-c]pyridine 
• 67-56-1 methanol 
• 259809-68-2 2-[(E)-2-Phenylethenyl]-4-vinyloxazole 
• 259809-69-3 2-{2-[(E)-2-Phenylethenyl]oxazol-4-yl}-1-ethanol 
• 259809-71-7 4-[2-(tert-butoxycarbonylamino)ethyl]-2-(trans-β-styryl)oxazole 
• 259809-72-8 5-(tert-butoxycarbonyl)-2-(trans-β-styryl)-4,5,6,7-tetrahydrooxazolo[5,4-c]pyridine 
• 259809-70-6 2-(2-{2-[(E)-2-Phenylethenyl]oxazol-4-yl}ethyl)-1H-isoindol-1,3(2H)-dione 
• 259809-67-1 2-[(E)-2-phenylethenyl]oxazole-4-carbaldehyde 

Relevant articles and documents

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Serine protease factor xa (fXa) inhibitor 1 showed good ex vivo anti-fXa activity upon oral administration in rats. However, it has been revealed that 1 had low metabolic stability against human liver microsomes. To improve the metabolic stability, we att

DIAMINE DERIVATIVES

A compound represented by formula (1):Q1-Q2-To-N(R1) -Q3-N(R2)-T1-Q4 [wherein R1 and R2 are hydrogen atoms or the like; Q1 is a saturated or unsaturated, 5- or 6- membered cyclic hydrocarbon group which may be substituted, or the like; Q2 is a single bond or the like; Q3 represents the following group: (wherein Q5 is an alkylene group having 1 to 8 carbon atoms, or the like); and T0 and T1 are carbonyl groups or the like], a salt thereof, a solvate thereof, or an N-oxide thereof. The compound is useful as an agent for preventing and/or treating cerebral infarction, cerebral embolism, myocardial infarction, angina pectoris, pulmonary infarction, pulmonary embolism, Buerger's disease, deep venous thrombosis, disseminated intravascular coagulation syndrome, thrombus formation after artificial valve or joint replacement, thrombus formation and reocclusion after angioplasty, systemic inflammatory response syndrome (SIRS), multiple organ dysfunction syndrome (MODS), thrombus formation during extracorporeal circulation, or blood clotting upon blood drawing.

ETHYLENEDIAMINE DERIVATIVES

The invention relates a compound represented by the formula (1):Q1-Q2-C(=O)-N(R1)-Q3-N(R2)-T1-Q4 wherein R1 and R2 represent H or the like; Q1 represents an aromatic ring, heterocyclic ring or the like; Q2 represents a single bond, aromatic ring, heterocyclic ring or the like; Q3 represents a group or the like, Q4 represents an aromatic ring, heterocyclic ring or the like; and T1 represents -CO- or -SO2-, and a medicine which comprises the compound and is useful for thrombosis and embolism.