26020-14-4

Basic information

• Product Name: b-D-Glucopyranosiduronic acid,(3b)-17-carboxy-28-norolean-12-en-3-yl
• Synonyms: 17β-Carboxy-28-norolean-12-en-3β-yl β-D-glucopyranosiduronic acid;Calenduloside E;Oleanolic acid 3-glucuronide;Oleanolic acid 3-O-glucuronide;Oleanolic acid 3-β-D-glucuronoside;Silphioside F;C08964;Oleanoic acid 3-o-glucuronide
• CAS NO: 26020-14-4
• Molecular Formula: C₃₆H₅₆O₉
• Molecular Weight: 632.82
• Product Categories: Pentacyclic Triterpenes;reagent;standard substance
• Mol File: 26020-14-4.mol
• Article Data: 6

Chemical Properties

• Melting Point: 243-245 °C (decomp)
• Boiling Point: 750.8±60.0 °C(Predicted)
• Appearance: /
• Density: 1.27±0.1 g/cm3(Predicted)
• PKA: 2.82±0.70(Predicted)
• CAS DataBase Reference: b-D-Glucopyranosiduronic acid,(3b)-17-carboxy-28-norolean-12-en-3-yl(CAS DataBase Reference)
• NIST Chemistry Reference: b-D-Glucopyranosiduronic acid,(3b)-17-carboxy-28-norolean-12-en-3-yl(26020-14-4)
• EPA Substance Registry System: b-D-Glucopyranosiduronic acid,(3b)-17-carboxy-28-norolean-12-en-3-yl(26020-14-4)

Safety Data

• Hazardous Substances Data: 26020-14-4(Hazardous Substances Data)

Usage

Uses

Oleanolic Acid 3-O-Glucuronide exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by inhibiting glucose transport at the brush border of the small intestine in oral glucose-loaded rats.

Upstream product

• 29014-88-8 saponin-D methylester 
• 80135-32-6 saponin-C methylester 
• 121521-92-4 3-O-{[β-D-glucopyranosyl (1->2)]-[α-L-arabinopyranosyl (1->3)]-β-D-glucuronopyranosyl}oleanolic acid 
• 96990-18-0 (3β)-17-carboxy-28-norolean-12-en-3-yl 3'-O-(β-D-xylopyranosyl)-β-D-glucuronide 
• 51415-02-2 chikusetsusaponin IVa 

Downstream Products

• 508-02-1 oleanolic acid 
• 489-91-8 D-glucuronic acid 
• 508-02-1 Oleanolic acid 
• 3391-81-9 androseptoside A 
• 6556-12-3 D-glucuronic acid 
• 196608-06-7 1-methoxyl glucuronate 6-methyl ester 
• 51724-38-0 (3β)-oleanolic acid 3-β-D-glucopyranosiduronic acid 6-methyl ester 
• 17681-01-5 methyl β-D-glucofuranosidurono-6,3-lactone 

Relevant articles and documents

Triterpenoid glycosides from the fruits of Kochia scoparia

From the fruits of Kochia scoparia (L.) Schrad, five triterpenoid glycosides were isolated for the first time from this plant. They were elucidated as momordin 1c, the 6'-methyl ester of momordin 1c, momordin IIc, 2'-O-β-D-glucopyranosylmomordin Ic, and 2'-O-β-D-glucopyranosylmomordin IIc on the basis of spectral and chemical methods. The last two saponins are new natural products.

SAPONINS FROM ROOTS OF MOMORDICA COCHINCHINENSIS

Ten minor saponins, momordins Ia-Ie and IIa-IIe, were isolated from the root of Momordica cochinchinensis, along with the known major saponins, momordins I and II.Their structures were established on the basis of chemical and spectroscopic analysis.The structures of the two new saponins were assigned as 3β-(((O-β-D-xylopyranosyl-(1-->2)-O-β-D-xylopyranosyl-(1-->3))O-β-D-glucopyranuronosyl)oxy)-olean-12-ene-28-oic acid for momordin Id and momordin Id-28-β-D-glucopyranosyl ester for momordin IId.It was confirmed that the genuine saponin present in the root was not the monodesmoside but the bisdesmoside, though the former is the major component in the dry root. Key word Index--Momordica cochinchinensis; Cucurbitaceae; saponin; momordin; oleanolic acid; monodesmoside; bisdesmoside; 13C NMR.

MOLLUSCICIDAL SAPONINS FROM SWARTZIA SIMPLEX

One monodesmosidic saponin and six bidesmosidic saponins have been isolated from the methanolic extract of the leaves of Swartzia simplex.They were shown to be glucuronides of oleanolic acid, gypsogenin and gypsogenic acid by chemical and spectral means.The monodesmosidic saponins exhibit various molluscicidal activities against the schistosomiasis-transmitting snail Biomphalaria glabrata. - Key Word Index: Swartzia simplex; Leguminosae; triterpene saponins; schistosomiasis; molluscicidal activity.