2611-01-0

Basic information

• Product Name: hexahydrobenzofuran-2(3H)-one
• Synonyms: 2-hydroxycyclohexylacetic acid lactone; hexahydro-2-benzofuran-1(3H)-one
• CAS NO: 2611-01-0
• Molecular Formula: C₈H₁₂O₂
• Molecular Weight: 140.1797
• Mol File: 2611-01-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 262.8°C at 760 mmHg
• Flash Point: 103.8°C
• Density: 1.093g/cm³
• Vapor Pressure: 0.0107mmHg at 25°C
• Refractive Index: 1.483
• CAS DataBase Reference: hexahydrobenzofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: hexahydrobenzofuran-2(3H)-one(2611-01-0)
• EPA Substance Registry System: hexahydrobenzofuran-2(3H)-one(2611-01-0)

Safety Data

• Hazardous Substances Data: 2611-01-0(Hazardous Substances Data)

Usage

Description

Hexahydrobenzofuran-2(3H)-one, also known as tetrahydro-3-furanone, is a colorless liquid with a slightly sweet, floral odor. It is a versatile chemical compound that serves as a solvent, flavoring agent, and precursor in various industrial applications.
Used in Perfume Industry:
Hexahydrobenzofuran-2(3H)-one is used as a solvent for the manufacturing of perfumes. Its sweet, floral odor makes it a valuable ingredient in creating various fragrances.
Used in Soap Industry:
In the soap industry, hexahydrobenzofuran-2(3H)-one is used as a solvent to help dissolve and mix various ingredients, ensuring a uniform and consistent product.
Used in Cosmetics Industry:
Hexahydrobenzofuran-2(3H)-one is used as a solvent in the production of cosmetics, aiding in the blending of different components and enhancing the overall quality of the final product.
Used as a Flavoring Agent in Food Industry:
Hexahydrobenzofuran-2(3H)-one is used as a flavoring agent in food products, providing a slightly sweet taste and enhancing the overall flavor profile.
Used as a Precursor in Pharmaceutical Industry:
Hexahydrobenzofuran-2(3H)-one is used as a precursor in the synthesis of pharmaceuticals, contributing to the development of new drugs and medications.
Used as a Precursor in Agrochemical Industry:
In the agrochemical industry, hexahydrobenzofuran-2(3H)-one is used as a precursor in the synthesis of various agrochemicals, such as pesticides and herbicides, to improve agricultural productivity.
It is important to handle and store hexahydrobenzofuran-2(3H)-one with care, as prolonged exposure to high concentrations may cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 85-44-9 phthalic anhydride 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 1687-30-5 cyclohexane-1,2-dicarboxylic acid 
• 2306-33-4 monoethyl phthalate 
• 87-41-2 2-benzofuran-1(3H)-one 
• 64-19-7 acetic acid 

Downstream Products

• 2105-40-0 (2-Methylcyclohexyl)methanol 
• 1233387-91-1 (3aR,7aS)-3a-(3,4-dichlorophenyl)octahydro-1H-isoindole 
• 1233387-90-0 (3aS,7aR)-3a-(3,4-dichlorophenyl)octahydro-1H-isoindole 
• 1450633-98-3 ethyl 2-(2-benzyloctahydro-1H-isoindol-1-yl)acetate 
• 1450633-97-2 (E)-ethyl3-(2-formylcyclohexyl)acrylate 
• 1450633-96-1 (E)-ethyl3-(2-(hydroxymethyl)cyclohexyl)acrylate 
• 1314593-98-0 C₁₅H₁₉Cl₂NO₂ 

Relevant articles and documents

Catalytic hydrogenation products of aromatic and aliphatic dicarboxylic acids

Hydrogenation of aromatic dicarboxylic acids gave 100 % selectivity to respective cyclohexane dicarboxylic acid with 5 % Pd/C catalyst. 5 % Ru/C catalyst was observed to give over hydrogenation products at 493 K and at lower temperature (453 K) the selectivity for cyclohexane dicarboxylic acids was increased. Hydrogenation of phthalic acid with Ru-Sn/Al2O3 catalyst was observed to give phthalide instead of 1,2-benzene dimethanol or 2-hydroxy methyl benzoic acid. Ru-Sn/Al2O3 catalyst selectively hydrogenated the carboxylic group of cyclohexane dicarboxylic acids to give cyclohexane dimethanol. Use of proper catalysts and reaction conditions resulted in desired products.