26110-91-8

Basic information

• Product Name: 1-tert-Butyl-4-(2,2-dimethylpropyl)benzol
• Synonyms: 1-tert-Butyl-4-(2,2-dimethylpropyl)benzol
• CAS NO: 26110-91-8
• Molecular Weight: 204.356
• Mol File: 26110-91-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-tert-Butyl-4-(2,2-dimethylpropyl)benzol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-Butyl-4-(2,2-dimethylpropyl)benzol(26110-91-8)
• EPA Substance Registry System: 1-tert-Butyl-4-(2,2-dimethylpropyl)benzol(26110-91-8)

Safety Data

• Hazardous Substances Data: 26110-91-8(Hazardous Substances Data)

Upstream product

• 927-83-3 di-t-butyldiazene 
• 98-51-1 4-tert-butyltoluene 
• 108-88-3 toluene 
• 35779-04-5 1-tert-butyl-4-iodobenzene 
• 38965-26-3 3,3-Dimethylbuttersaeureanhydrid 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 1710-98-1 p-tert-butyl benzoyl chloride 
• 22583-66-0 1-(4-(tert-butyl)phenyl)-2,2-dimethylpropan-1-one 
• 86439-83-0 DL-3,4-Bis(4-tert-butylphenyl)-2,2,5,5-tetramethylhexan 
• 345948-38-1 meso-3,4-Bis(4-tert-butylphenyl)-2,2,5,5-tetramethylhexan 
• 594-19-4 tert.-butyl lithium 
• 19692-45-6 4-tert-butylbenzyl chloride 
• 34235-16-0 1-(4-tert-Butylphenyl)-2,2-dimethyl-1-propanol 
• 3972-65-4 1-bromo-4-tert-butylbenzene 

Relevant articles and documents

Nickel-Catalyzed Decarboxylative Alkylation of Aryl Iodides with Anhydrides

We present the anhydride-based decarboxylative alkylation of aryl iodides catalyzed by nickel. This method of decarboxylative coupling works with a broad scope of aliphatic carboxylic anhydrides and tolerates synthetically useful aromatic substituents. Assisted by a redox system of pyridine N-oxide and zinc additives, the current reaction occurs under mild conditions and without the assistance of photocatalyst. Notably, this method features high chemoselectivity toward alkyl migration with mixed aliphatic/aromatic anhydrides. Thus, it provides a powerful synthetic tool to modify high-valued aliphatic carboxylic acids by converting them into mixed anhydrides using readily available aryl carboxylic acids such as p-toluic acid. We propose a catalytic cycle that involves the key steps of free radical-based decarboxylation and subsequent alkyl transfer to nickel that precedes an oxidatively induced C-C reductive elimination from Ni(III).

Chemistry of the tert-Butyl Radical: Polar Character, ρ Value for Reaction with Toluenes, and the Effect of Radical Polarity on the Ration of Benzylic Hydrogen Abstraction to Addition to Aromatic Rings

We have reexamined the reactions of tert-butyl radicals with toluenes and have obtained a ρ value of 0.49 +/- 0.04 at 80 deg C.The new, independent system involves the quantification of all of the principal products from the reaction of tert-butyl radicals with mixtures of toluene and substituted toluene.Five major products contain benzyl fragments and are formed in significant yields: two symmetrical bibenzyls, the cross bibenzyl, and the two neopentylbenzenes that result from combination of tert-butyl and the two benzyl radicals.Attack on the side chain is a major reaction of free tert-butyl radicals and is the only significant reaction that they undergo other than cage and termination reactions. tert-Butyl radicals do not add to the ring of toluenes.Data on the relative rates of addition to benzenes and hydrogen abstraction from toluenes are collected for a series of radicals including hydrogen atoms; methyl, isopropyl, and tert-butyl radicals; and p-nitrophenyl, p-bromophenyl, and phenyl radicals.The data demonstrate that more electrophilic radicals have a larger tendency to add to rings whereas more nucleophilic radicals have a larger tendency to abstract benzylic hydrogens.