26121-57-3

Basic information

• Product Name: 2-hydroxy-12-methoxypicrasa-2,12-diene-1,11,16-trione
• CAS NO: 26121-57-3
• Molecular Formula: C₂₁H₂₆O₆
• Molecular Weight: 374.4275
• Mol File: 26121-57-3.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 601.3°C at 760 mmHg
• Flash Point: 212.9°C
• Density: 1.29g/cm³
• Vapor Pressure: 5.76E-17mmHg at 25°C
• Refractive Index: 1.575
• CAS DataBase Reference: 2-hydroxy-12-methoxypicrasa-2,12-diene-1,11,16-trione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-12-methoxypicrasa-2,12-diene-1,11,16-trione(26121-57-3)
• EPA Substance Registry System: 2-hydroxy-12-methoxypicrasa-2,12-diene-1,11,16-trione(26121-57-3)

Safety Data

• Hazardous Substances Data: 26121-57-3(Hazardous Substances Data)

Upstream product

• 26121-56-2 nigakilactone I 
• 139276-58-7 Isopicrasin B 
• 76-78-8 quassin 
• 139276-57-6 2,12-Dimethoxy-1β-hydroxy-2,12-picradiene-11,16-dione 16-ethylene acetal 
• 139276-56-5 2,12-Dimethoxy-2,12-picradiene-1,11,16-trione 16-(ethylene ketal) 
• 83543-82-2 picrasinoside-A 
• 26121-56-2 (+)-picrasin B 
• 123834-65-1 1β,11β-dihydroxy-16α-methoxy-9β-picrasan-12-one 
• 127897-11-4 (3aR,5R,6aR,7aS,8R,11aS,11bS,11cS)-5-Hydroxy-2-methoxy-3,8,11a,11c-tetramethyl-3a,4,5,6a,7,7a,8,9,10,11a,11b,11c-dodecahydro-6-oxa-benzo[de]anthracene-1,11-dione 
• 123834-66-2 12-hydroxy-16α-methoxypicras-12-en-1,11-dione 
• 123834-85-5 12,16α-dimethoxypicras-12-en-1,11-dione 
• 26121-56-2 picrasin B 
• 123834-73-1 1β,11β-diacetoxy-20-((phenoxythiocarbonyl)oxy)-16-methoxy-9β-picrasan-12-one 
• 123857-39-6 1β,11β-diacetoxy-16β-methoxy-9β-picrasan-12-one 

Downstream Products

• 26121-56-2 (+)-picrasin B 
• 30315-04-9 (-)-picrasin B acetate 
• 30315-04-9 Acetic acid (3aR,6aR,7aS,8R,10S,11aS,11bS,11cS)-2-methoxy-3,8,11a,11c-tetramethyl-1,5,11-trioxo-1,3a,4,5,6a,7,7a,8,9,10,11,11a,11b,11c-tetradecahydro-6-oxa-benzo[de]anthracen-10-yl ester 
• 26121-56-2 nigakilactone I 
• 210623-98-6 Benzoic acid (3aR,6aR,7aS,8S,11aS,11bS,11cS)-2-methoxy-3,8,11a,11c-tetramethyl-1,5,11-trioxo-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c-dodecahydro-6-oxa-benzo[de]anthracen-10-yl ester 
• 76-78-8 quassin 
• 76-78-8 quassin 

Relevant articles and documents

Semisynthetic derivatives of quassin

The natural product quassin has been modified in order to produce compounds with potential antimalarial action. The modifications include demethylation, reduction of the keto function, esterification with simple organic acids and - to enhance the uptake through the biological barriers and increase the stability of the compounds - with lipoamino acids.

An Enantioselective Synthesis of (+)-Picrasin B, (+)-Δ2-Picrasin B, and (+)-Quassin from the R-(-) Enantiomer of the Wieland-Miescher Ketone

An enantioselective total synthesis of (+)-picrasin B (1), (+)-Δ2-picrasin B (11), and (+)-quassin (12) from the R-(-) enantiomer of the Wieland-Miescher ketone (3) employed an A-AB-ABC-ABCD sequence to assemble the tetracyclic skeleton.The cru

New quassinoid glucosides, picrasinoside-A, -B, -C, -D, -E, -F, and -G and new hemiacetals, picrasinol-A and -B, from the stem bark of Picrasma ailanthoides Planchon

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