26131-82-8

Basic information

• Product Name: 2-Cyclopenten-1-one, 5-methyl-3-phenyl-
• Synonyms: (+/-)-5-methyl-3-phenyl-cyclopent-2-enone;5-Methyl-3-phenyl-2-cyclopenten-1-one;2-Cyclopenten-1-one,5-methyl-3-phenyl
• CAS NO: 26131-82-8
• Molecular Formula: C12H12O
• Molecular Weight: 172.227
• Mol File: 26131-82-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-Cyclopenten-1-one, 5-methyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one, 5-methyl-3-phenyl-(26131-82-8)
• EPA Substance Registry System: 2-Cyclopenten-1-one, 5-methyl-3-phenyl-(26131-82-8)

Safety Data

• Hazardous Substances Data: 26131-82-8(Hazardous Substances Data)

Upstream product

• 878549-72-5 2-methyl-4-phenylcyclopenta-1,4-dien-1-yl acetate 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 878549-71-4 4-methyl-1-phenylpent-4-en-2-yn-1-yl acetate 
• 591-51-5 phenyllithium 
• 22627-70-9 3-ethoxycyclopent-2-en-1-one 
• 137935-62-7 methyl-4 phenyl-1 penten-4 yn-2 ol-1 
• 3810-26-2 3-phenyl-2-cyclopenten-1-one 
• 74-88-4 methyl iodide 
• 70-11-1 α-bromoacetophenone 
• 111400-48-7 ethyl 2-acetyl-2-methyl-4-oxo-4-phenylbutanoate 
• 3728-07-2 1-Dimethylamino-2-methyl-5-phenyl-pent-4-en-3-on 

Downstream Products

• 56542-44-0 Hydroxy-2 methyl-5 phenyl-3 cyclopenten-2 on 

Relevant articles and documents

Gold-Catalyzed Cycloisomerization–Halogenation Sequence of 1,3-Enyne Esters with NXS: Efficient Synthesis of 5-Bromo/Iodo Cyclopentenones

An efficient synthetic approach for the synthesis of 5-bromo/iodo-cyclopentenones containing a C–X (Br, I) stereocenter that relies on gold(I)-catalyzed cycloisomerization–electrophilic halogenation sequence of 1,3-enyne esters with N-bromosuccinimide (NB

Gold(I)-Catalyzed Tandem Cycloisomerization and Fluorination of 1,3(4)-Enyne Esters with NFSI: One-Pot Assembly of 5-Fluoro- Cyclopentenones

An efficient synthetic approach for the synthesis of 5-fluoro-cyclopentenones containing a fluorine-substituted carbon stereocenter that relies on gold(I)-catalyzed cycloisomerization and fluorination sequence of 1,3(4)-enyne esters with N-fluorbenzensulfonimide (NFSI) is described. This tandem transformation exhibited a broad substrate scope and excellent functional group compatibility, providing a novel protocol for rapid assembly 5-fluoro-cyclopentenones in good to excellent yields under mild reaction conditions. The mechanistic studies revealed that the transformation involves a gold-catalyzed cycloisomerization and electrophilic fluorination cascade to give the 5-fluoro-cyclopentenones. (Figure presented.).

Dynamic kinetic resolution via asymmetric conjugate reduction: Enantio- and diastereoselective synthesis of 2,4-dialkyl cyclopentanones

Herein, we report the kinetic and the dynamic kinetic resolutions of racemic 3,5-dialkyl-2-cyclopenten-1-ones. Kinetic resolution, with good selectivity factors (25-52), was achieved by conjugate reduction with catalytic CuCl/NaOt-Bu/(S)-p-tol-BINAP and s