261381-22-0

Basic information

• Product Name: methyl 4-([1-13C]-α-bromoacetyl)salicylate
• Synonyms: methyl 4-([1-13C]-α-bromoacetyl)salicylate
• CAS NO: 261381-22-0
• Molecular Weight: 274.072
• Mol File: 261381-22-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 4-([1-13C]-α-bromoacetyl)salicylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-([1-13C]-α-bromoacetyl)salicylate(261381-22-0)
• EPA Substance Registry System: methyl 4-([1-13C]-α-bromoacetyl)salicylate(261381-22-0)

Safety Data

• Hazardous Substances Data: 261381-22-0(Hazardous Substances Data)

Upstream product

• 119-36-8 methyl salicylate 
• 261381-21-9 C₉⁽¹³⁾CH₁₀O₄ 

Downstream Products

• 261381-23-1 C₃₂⁽¹³⁾CH₄₁NO₅ 
• 1025930-27-1 C₃₁⁽¹³⁾CH₄₀⁽²⁾H₃NO₄ 

Relevant articles and documents

Improved synthesis of 13C,2H3- and 2H3-salmeterol by Cs2CO3-mediated monoalkylation of a primary amine

An abbreviated synthesis of isotopically labelled salmeterol has been achieved. The key improvement utilizes a highly selective Cs2CO3-mediated one-pot alkylation of benzylamine by 6-bromo-1-(4′-phenylbutoxy)hexane to prepare the limiting reagent, 6-N-benzylamino-1-(4′-phenylbutoxy)hexane without overalkylation. The method was applied to synthesis of the title compounds in >97 at% isotopic purity. Copyright