261911-55-1

Basic information

• Product Name: (4S)-N-(o-(benzyloxy)phenyl)-4-hydroxy-5-methoxypentanamide
• Synonyms: (4S)-N-(o-(benzyloxy)phenyl)-4-hydroxy-5-methoxypentanamide
• CAS NO: 261911-55-1
• Molecular Weight: 329.396
• Mol File: 261911-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4S)-N-(o-(benzyloxy)phenyl)-4-hydroxy-5-methoxypentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-N-(o-(benzyloxy)phenyl)-4-hydroxy-5-methoxypentanamide(261911-55-1)
• EPA Substance Registry System: (4S)-N-(o-(benzyloxy)phenyl)-4-hydroxy-5-methoxypentanamide(261911-55-1)

Safety Data

• Hazardous Substances Data: 261911-55-1(Hazardous Substances Data)

Upstream product

• 20012-63-9 o-(benzyloxy)aniline 
• 96845-45-3 (S)-(+)-5-methoxymethyl-2-oxotetrahydrofuran 

Downstream Products

• 261911-57-3 (5R)-1-(o-tert-butyldiphenylsiloxyphenyl)-5-(methoxymethyl)-2-pyrrolidinone 
• 261911-68-6 (3R,5R)-3-benzoyloxy-1-(ortho-hydroxy)phenyl-5-methoxymethyl-2-pyrrolidinone 
• 261911-56-2 (5R)-1-(o-(benzyloxy)phenyl)-5-(methoxymethyl)-2-pyrrolidinone 

Relevant articles and documents

Synthesis of optically active 5-substituted-2-pyrrolidinone derivatives having atropisomeric structure and 3,5-cis-selective reaction of their enolates with electrophiles

Optically pure forms (≥98% ee) of N-(o-tert-butylphenyl)-5- (methoxymethyl)-2-pyrrolidinone having atropisomerism and N-(o-tert- butyldiphenylsiloxyphenyl)-5-(methoxymethyl)-2-pyrrolidinone having an atropisomerism-like structure were prepared from ortho-substituted aniline derivatives and (S)-5-(methoxymethyl)butyrolactone in a stereoselective manner. The reactions of Li-enolates from these lactams with various electrophiles and subsequent dearylation of the products gave 3,5-cis- disubstituted-2-pyrrolidinone derivatives.