2620-82-8

Basic information

• Product Name: 1H-Benzimidazole, 2-(4-methoxyphenyl)-1-methyl-
• CAS NO: 2620-82-8
• Molecular Formula: C15H14N2O
• Molecular Weight: 238.289
• Mol File: 2620-82-8.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 1H-Benzimidazole, 2-(4-methoxyphenyl)-1-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Benzimidazole, 2-(4-methoxyphenyl)-1-methyl-(2620-82-8)
• EPA Substance Registry System: 1H-Benzimidazole, 2-(4-methoxyphenyl)-1-methyl-(2620-82-8)

Safety Data

• Hazardous Substances Data: 2620-82-8(Hazardous Substances Data)

Usage

Chemical class

1H-Benzimidazole, 2-(4-methoxyphenyl)-1-methylbelongs to the benzimidazole class of chemicals.

Use in pharmaceutical industry

It is used as a building block in the synthesis of various pharmaceutical drugs.

Potential biological activities

It has been studied for its potential biological activities and has been identified as a potential drug candidate for the treatment of various diseases, including cancer, inflammation, and neurological disorders.

Antimicrobial and antifungal properties

It has been investigated for its antimicrobial and antifungal properties.

Versatility

1H-Benzimidazole, 2-(4-methoxyphenyl)-1-methylis a versatile chemical with potential applications in various industries.

Upstream product

• 4760-34-3 N-methyl-1,2-phenylenediamine 
• 105-13-5 4-Methoxybenzyl alcohol 
• 123-11-5 4-methoxy-benzaldehyde 
• 6504-13-8 4-(1H-benzimidazol-2-yl)phenol 
• 74-88-4 methyl iodide 
• 1632-83-3 1-Methylbenzimidazole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 623-12-1 4-chloromethoxybenzene 
• 7305-10-4 4-methoxyphenyl dimethylcarbamate 
• 2393-23-9 4-methoxy-benzylamine 
• 33402-67-4 sodium hydroxy(4-methoxyphenyl)methanesulfonate 
• 2620-81-7 2-(4-methoxyphenyl)-1H-benzimidazole 
• 95-54-5 1,2-diamino-benzene 
• 100-09-4 4-methoxybenzoic acid 

Relevant articles and documents

Preparation of 2-substituted benzimidazoles and related heterocycles directly from activated alcohols using TOP methodology

A one-pot procedure for preparing 2-substituted benzimidazoles directly from activated alcohols in good to excellent yields using a new Tandem Oxidation Process (TOP) is reported. The use of this methodology to prepare 2-substituted benzoxazoles and 2-substituted benzothiazoles is also described.

Ruthenium-Catalyzed ortho- And meta-H/D Exchange of Arenes

Ruthenium-catalyzed aromatic H/D exchange in [D4]acetic acid has been developed. By using N-heteroarenes as directing groups, both ortho and meta positions are selectively deuterated with high levels of D incorporation. Moreover, this strategy provides an alternative way to achieve meta-C-H activation.

Intramolecular C(sp3)–H Imination towards Benzimidazoles Using Tetrabutylammonium Iodide and tBuOOH

Development of sustainable and economically viable methods is challenging but desired in organic synthesis. Herein, intramolecular C(sp3)–H imination between a free amine group and N-methylene group is established using TBAI (20 mol %)-TBHP (3.0 equiv.) in DMSO which is found to be an inexpensive replacement of PhI-mCPBA in HFIP.