26241-51-0 Usage
Description
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione is a tetracyclic triterpenoid compound characterized by its unique molecular structure. It features a 4,4,8-trimethylandrosta-1,14-diene core with oxo groups at positions 3 and 16, an acetoxy group at position 7, and a furan-3-yl group at position 17. (13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione is isolated from the Azadirachta indica plant, commonly known as the Neem tree, and exhibits a range of biological activities, including antimycobacterial and anti-inflammatory properties.
Uses
Used in Pharmaceutical Industry:
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione is used as a pharmaceutical agent for its antimycobacterial properties. It can be employed in the development of treatments for various mycobacterial infections, including tuberculosis, by targeting and inhibiting the growth of mycobacteria.
Used in Anti-inflammatory Applications:
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione is also used for its anti-inflammatory effects, making it a potential candidate for the development of anti-inflammatory drugs. It can be utilized in the treatment of various inflammatory conditions, such as arthritis, asthma, and other autoimmune diseases, by reducing inflammation and alleviating symptoms.
Used in Antifungal Applications:
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione exhibits antifungal properties, which can be harnessed in the development of antifungal agents. It can be used to treat various fungal infections, such as candidiasis, aspergillosis, and other systemic mycoses, by inhibiting the growth and proliferation of fungi.
Used in Cosmetic Industry:
Due to its anti-inflammatory and antimicrobial properties, (13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione can be used in the cosmetic industry for the development of skincare products. It can be incorporated into creams, lotions, and other formulations to help reduce inflammation, soothe irritated skin, and protect against microbial infections.
Used in Agricultural Industry:
(13α,17α)-7α-Acetoxy-21,23-epoxy-4,4,8-trimethyl-24-nor-5α-chola-1,14,20,22-tetrene-3,16-dione's antimicrobial properties can also be applied in the agricultural industry for the development of biopesticides and fungicides. It can be used to control the growth of harmful fungi and bacteria that affect crop yields and quality, thereby contributing to more sustainable and efficient agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 26241-51-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,6,2,4 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 26241-51:
(7*2)+(6*6)+(5*2)+(4*4)+(3*1)+(2*5)+(1*1)=90
90 % 10 = 0
So 26241-51-0 is a valid CAS Registry Number.
InChI:InChI=1/C28H34O5/c1-16(29)33-23-14-20-25(2,3)22(31)8-11-26(20,4)19-7-10-27(5)21(28(19,23)6)13-18(30)24(27)17-9-12-32-15-17/h8-9,11-13,15,19-20,23-24H,7,10,14H2,1-6H3/t19-,20+,23-,24-,26-,27-,28?/m1/s1
26241-51-0Relevant articles and documents
NIMBOCINOL AND 17-EPINIMBOCINOL FROM THE NIMBIDIN FRACTION OF NEEM OIL
Gaikwad, Balasaheb R.,Mayelvaganan, T.,Vyas, Brahamanand A.,Bhat, Sujata V.
, p. 3963 - 3965 (2007/10/02)
A new tetranortriterpene alcohol has been isolated from nimbidin fraction of the methanol extract of neem oil.Its structure was established by spectral studies and conversion to 17-epiazadiradione by acetylation.
Studies on the Chemical Constituents of Azadirachta indica A.Juss (Meliaceae), Part VII
Siddiqui, Salimuzzaman,Faizi, Shaheen,Siddiqui, Bina Shaheen
, p. 922 - 924 (2007/10/02)
A new limonoid, nimbocinol, has been isolated from the fresh, undried, ripe fruits of Azadirachta indica (neem) along with known components, azadirone, epoxyazadiradione, azadiradione, gedunin, 17-hydroxyazadiradione and cholesterol.It is the first report of the isolation of cholesterol from any part of the neem tree. - Key words: Azadirachta indica, Meliaceae, 7-Deacetoxy-7α-hydroxyazadiradione
