262426-54-0

Basic information

• Product Name: Acetic acid, [(4-formyl-2-nitrophenyl)thio]-, methyl ester
• CAS NO: 262426-54-0
• Molecular Formula: C10H9NO5S
• Molecular Weight: 255.251
• Mol File: 262426-54-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Acetic acid, [(4-formyl-2-nitrophenyl)thio]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, [(4-formyl-2-nitrophenyl)thio]-, methyl ester(262426-54-0)
• EPA Substance Registry System: Acetic acid, [(4-formyl-2-nitrophenyl)thio]-, methyl ester(262426-54-0)

Safety Data

• Hazardous Substances Data: 262426-54-0(Hazardous Substances Data)

Upstream product

• 2365-48-2 Methyl thioglycolate 
• 16588-34-4 4-chloro-3-nitro-benzaldehyde 
• 121-92-6 3-nitrobenzoic acid 
• 709-58-0 1-nitro-3-(trichloromethyl)benzene 

Relevant articles and documents

5-Quinoline derivatives having an anti-bacterial activity

The present invention describes novel anti-bacterial compounds of the formula (I). These compounds are, amongst others, of interest as inhibitors of DNA gyrase and topoisomerases, for example of topoisomerase II and IV.

Tele nucleophilic aromatic substitutions in 1-nitro-3- and 1,3-dinitro- 5-trichloromethylbenzene, and 3-trichloromethylbenzonitrile. A new synthesis of the 1,4-benzothiazine-3(4H)-one ring system from 3 nitrobenzoic acid

3-Trichloromethylnitrobenzene 2, 1,3-dinitro-5-trichloromethylbenzene 13 and 3-trichloromethylbenzonitrile 18 react with sodium methoxide to give 4- methoxy-3-nitrobenzaldehyde 6, 4-methoxy-3,5-dinitrobenzaldehyde 15 and 5- dimethoxymethyl-2-methoxybenzonitrile 19, respectively. Compounds 2 and 13 react with methyl thioglycolate to afford dichloromethylacetates 7 and 16, respectively. These products are the result of tele nucleophilic aromatic substitution. Compound 18 reacted with methyl thioglycolate to give acetate 20 resulting from nucleophilic displacement of cyanide. Reductive cyclisation of 7 afforded benzothiazine 11. (C) 2000 Elsevier Science Ltd.